product summary
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company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Synaptophysin monoclonal antibody (SP15)
catalog :
ADI-VAM-SV011-F
quantity :
200 µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SP15
reactivity :
Pacific electric ray, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, proximity ligation assay
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • proximity ligation assay; rat; 1:3000; loading ...; fig 2a
  • western blot; rat; 1:10,000; loading ...; fig 3a
Lundgren J, Vandermeulen L, Sandebring Matton A, Ahmed S, Winblad B, Di Luca M, et al. Proximity ligation assay reveals both pre- and postsynaptic localization of the APP-processing enzymes ADAM10 and BACE1 in rat and human adult brain. BMC Neurosci. 2020;21:6 pubmed publisher
  • western blot; mouse; loading ...; fig 3a
Croft C, Wade M, Kurbatskaya K, Mastrandreas P, Hughes M, Phillips E, et al. Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures. Cell Death Dis. 2017;8:e2671 pubmed publisher
  • immunocytochemistry; Pacific electric ray; 1:200; fig 3
Schedin Weiss S, Caesar I, Winblad B, Blom H, Tjernberg L. Super-resolution microscopy reveals ?-secretase at both sides of the neuronal synapse. Acta Neuropathol Commun. 2016;4:29 pubmed publisher
Choi S, Baek J, Zuo X, Kim S, Dunaief J, Lipschutz J. Cdc42 and sec10 Are Required for Normal Retinal Development in Zebrafish. Invest Ophthalmol Vis Sci. 2015;56:3361-70 pubmed publisher
Turman J. The development of mastication in rodents: from neurons to behaviors. Arch Oral Biol. 2007;52:313-6 pubmed
Honer W, Hu L, Davies P. Human synaptic proteins with a heterogeneous distribution in cerebellum and visual cortex. Brain Res. 1993;609:9-20 pubmed
product information
Product ID :
ADI-VAM-SV011
Catalog Number :
ADI-VAM-SV011-F
Product Name :
Synaptophysin monoclonal antibody (SP15)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
200 µl
list of Pubmed id :
17055446, 7685234
Clone :
SP15
Isotype :
IgM
SPECIES REACTIVITY :
Human, Mouse, Rat, Bovine
Background :
Synaptophysin is an integral membrane protein involved in neurotransmitter exocytosis. This protein consists of four transmembrane domains, with its N- and C-terminus facing the cytoplasm. Studies have shown Synaptophysin to be a major cholesterol-binding protein in brain synaptic vesicles.
ALTnames :
SYP
Immunogen :
Synaptic vesicle-containing fractions immunoprecipitated from human brain homogenates using anti-human Synaptophysin mAb antibodies.
Buffer :
Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Uses :
Detects a band of ~38kDa by Western blot.
Application Summary :
IHC, WB
Storage :
-20°C
more info or order :
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.