SAP97 monoclonal antibody (RPI 197.4) | Enzo Life Sciences ADI-VAM-PS005-F product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

SAP97 monoclonal antibody (RPI 197.4)

catalog :

ADI-VAM-PS005-F

quantity :

200 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

RPI 197.4

reactivity :

mouse, pigs

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Enzo Life Sciences product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; mouse immunocytochemistry; mouse western blot; mouse	Underhill S, Wheeler D, Amara S. Differential regulation of two isoforms of the glial glutamate transporter EAAT2 by DLG1 and CaMKII. J Neurosci. 2015;35:5260-70 pubmed publisher
immunohistochemistry; pigs ; 1:100 western blot; pigs ; 1:1000	Park D, Cerrone M, Morley G, Vasquez C, Fowler S, Liu N, et al. Genetically engineered SCN5A mutant pig hearts exhibit conduction defects and arrhythmias. J Clin Invest. 2015;125:403-12 pubmed publisher
	Yokoyama T, Saino T, Nakamuta N, Kusakabe T, Yamamoto Y. Three-dimensional architectures of P2X2-/P2X3-immunoreactive afferent nerve terminals in the rat carotid body as revealed by confocal laser scanning microscopy. Histochem Cell Biol. 2016;146:479-88 pubmed publisher
	Heise C, Schroeder J, Schoen M, Halbedl S, Reim D, Woelfle S, et al. Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus. Front Cell Neurosci. 2016;10:106 pubmed publisher
	Vicidomini C, Ponzoni L, Lim D, Schmeisser M, Reim D, Morello N, et al. Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice. Mol Psychiatry. 2017;22:689-702 pubmed publisher
	Jimeno D, Gómez C, Calzada N, de la Villa P, Lillo C, Santos E. RASGRF2 controls nuclear migration in postnatal retinal cone photoreceptors. J Cell Sci. 2016;129:729-42 pubmed publisher
	KÃ¶rber C, Horstmann H, Venkataramani V, HerrmannsdÃ¶rfer F, Kremer T, Kaiser M, et al. Modulation of Presynaptic Release Probability by the Vertebrate-Specific Protein Mover. Neuron. 2015;87:521-33 pubmed publisher
	Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen J, et al. Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease. Nat Neurosci. 2015;18:826-35 pubmed publisher
	Chand K, Lee K, Schenning M, Lavidis N, Noakes P. Loss of Î²2-laminin alters calcium sensitivity and voltage-gated calcium channel maturation of neurotransmission at the neuromuscular junction. J Physiol. 2015;593:245-65 pubmed publisher
	Takaki F, Nakamuta N, Kusakabe T, Yamamoto Y. Sympathetic and sensory innervation of small intensely fluorescent (SIF) cells in rat superior cervical ganglion. Cell Tissue Res. 2015;359:441-451 pubmed publisher
	Wu F, Li R, Umino Y, Kaczynski T, Sapkota D, Li S, et al. Onecut1 is essential for horizontal cell genesis and retinal integrity. J Neurosci. 2013;33:13053-65, 13065a pubmed publisher
	Taylor A, Wu J, Tai H, Schuman E. Axonal translation of ?-catenin regulates synaptic vesicle dynamics. J Neurosci. 2013;33:5584-9 pubmed publisher
	Djakovic S, Marquez Lona E, Jakawich S, Wright R, Chu C, Sutton M, et al. Phosphorylation of Rpt6 regulates synaptic strength in hippocampal neurons. J Neurosci. 2012;32:5126-31 pubmed publisher
	Chen J, Mizushige T, Nishimune H. Active zone density is conserved during synaptic growth but impaired in aged mice. J Comp Neurol. 2012;520:434-52 pubmed publisher
	Schrof S, Staudt T, Rittweger E, Wittenmayer N, Dresbach T, Engelhardt J, et al. STED nanoscopy with mass-produced laser diodes. Opt Express. 2011;19:8066-72 pubmed publisher
	Epis R, Marcello E, Gardoni F, Longhi A, Calvani M, Iannuccelli M, et al. Modulatory effect of acetyl-L-carnitine on amyloid precursor protein metabolism in hippocampal neurons. Eur J Pharmacol. 2008;597:51-6 pubmed publisher
	Lee S, Fan S, Makarova O, Straight S, Margolis B. A novel and conserved protein-protein interaction domain of mammalian Lin-2/CASK binds and recruits SAP97 to the lateral surface of epithelia. Mol Cell Biol. 2002;22:1778-91 pubmed
	Mehta S, Wu H, Garner C, Marshall J. Molecular mechanisms regulating the differential association of kainate receptor subunits with SAP90/PSD-95 and SAP97. J Biol Chem. 2001;276:16092-9 pubmed

product information

Product ID :

ADI-VAM-PS005

Catalog Number :

ADI-VAM-PS005-F

Product Name :

SAP97 monoclonal antibody (RPI 197.4)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

200 µg

list of Pubmed id :

18801359, 11865057, 11279111

Clone :

RPI 197.4

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Mouse, Rat, Dog

Background :

Synapse-associated proteins SAP97 and SAP102 display extensive sequence homology to the PSD 95 family of proteins that facilitate ion channel clustering at synaptic terminals. In addition to the CNS, SAP97 is also detected at the basal lateral membrane between a variety of epithelial cells. SAP102 associates with NMDA receptors through the C-terminal NR2B subunit of the receptor. The N-terminal SAP97 PDZ domain mediates its interaction with the synaptic ras-GTPase activating protein SynGAP.

ALTnames :

Synapse-associated protein 97, Disks large homolog 1

Immunogen :

Recombinant rat SAP97 (N-terminal fragment).

Buffer :

Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects bands of ~97kDa and ~140kDa by Western blot.

Application Summary :

ICC, IHC, IP, WB, Electron microscopy

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage