UNC45a monoclonal antibody (AbS1) | Enzo Life Sciences ADI-SRA-1800-F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

UNC45a monoclonal antibody (AbS1)

catalog :

ADI-SRA-1800-F

quantity :

200 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AbS1

application :

western blot

product information

Product ID :

ADI-SRA-1800

Catalog Number :

ADI-SRA-1800-F

Product Name :

UNC45a monoclonal antibody (AbS1)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

200 µg

Clone :

AbS1

Isotype :

IgG2b

SPECIES REACTIVITY :

Human, Mouse, Rat

Background :

GC UNC45 (general cell UNC45/unc45a) is an Hsp90 co-chaperone that has been shown to play a critical role in the chaperoning of myosin proteins as well as the progesterone receptor (PR). There are two known vertebrate isoforms of UNC45 that are functional orthologs of the C. elegans unc-45, an important protein in the development of organized body wall muscles. The vertebrate general cell form (GC UNC45/unc45a) is ubiquitously expressed, while the striated muscle-specific isoform (SM UNC45/unc45b) is found in cardiac and skeletal muscle. In vitro, GC UNC45 preferentially binds the Hsp90 beta isoform, and is specifically required for proper cellular distribution of Hsp90β but not Hsp90α.

Immunogen :

Recombinant human UNC45.

Buffer :

Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects a band of ~98kDa by Western blot.

Application Summary :

Storage :

-20°C