FKBP59 monoclonal antibody (KN382/EC1) | Enzo Life Sciences ADI-SRA-1400-D product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

FKBP59 monoclonal antibody (KN382/EC1)

catalog :

ADI-SRA-1400-D

quantity :

50 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

KN382/EC1

reactivity :

human, mouse, bovine

application :

western blot, immunohistochemistry, immunoprecipitation

citations: 3

Reference
Tsutsumi S, Mollapour M, Graf C, Lee C, Scroggins B, Xu W, et al. Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain. Nat Struct Mol Biol. 2009;16:1141-7 pubmed publisher
Guo Y, Guettouche T, Fenna M, Boellmann F, Pratt W, Toft D, et al. Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex. J Biol Chem. 2001;276:45791-9 pubmed
Gold B, Densmore V, Shou W, Matzuk M, Gordon H. Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506. J Pharmacol Exp Ther. 1999;289:1202-10 pubmed

product information

Product ID :

ADI-SRA-1400

Catalog Number :

ADI-SRA-1400-D

Product Name :

FKBP59 monoclonal antibody (KN382/EC1)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

50 µg

list of Pubmed id :

19838189, 11583998, 10336507

Clone :

KN382/EC1

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Mouse, Rabbit, Monkey, Mink, Hamster, Guinea pig, Bovine

Background :

FKBP59, also known as Hsp56/p59 is an immunophilin that is a component of Hsp70/Hsp90/steroid receptor complexes. Expression of FKBP59 is increased in response to heat shock and ischemic stress, and is thought to play a role in the folding and cytoplasmic/nuclear distribution of steroid receptors.

ALTnames :

HSP56, Heat shock protein 56, FK506 binding protein 1A

Immunogen :

Partially purified 9S rabbit uterine progesterone receptor.

Buffer :

Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects a band of ~59kDa by Western blot.

Application Summary :

IHC, IP, WB

Storage :

-20°C