Grp75/Mortalin monoclonal antibody (30A5) | Enzo Life Sciences ADI-SPS-825-D product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Grp75/Mortalin monoclonal antibody (30A5)

catalog :

ADI-SPS-825-D

quantity :

50 µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

30A5

The same clone is also sold as:

Novus Biologicals: NBP1-97448-0.05ml
Invitrogen: MA1-91639

reactivity :

human, mouse, rat, dogs, chicken, bovine

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

Enzo Life Sciences product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 1	Cook T, Hoekstra J, Eaton D, Zhang J. Mortalin is Expressed by Astrocytes and Decreased in the Midbrain of Parkinson's Disease Patients. Brain Pathol. 2016;26:75-81 pubmed publisher
western blot; human; fig 1	Klaus C, Kaemmerer E, Reinartz A, Schneider U, Plum P, Jeon M, et al. TP53 status regulates ACSL5-induced expression of mitochondrial mortalin in enterocytes and colorectal adenocarcinomas. Cell Tissue Res. 2014;357:267-78 pubmed publisher
immunohistochemistry - paraffin section; rat; 1:1000 western blot; rat; 1:1000	Fedorova L, Tamirisa A, Kennedy D, Haller S, Budnyy G, Shapiro J, et al. Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach. BMC Nephrol. 2013;14:209 pubmed publisher
	Strnad P, Tao G, So P, Lau K, Schilling J, Wei Y, et al. "Toxic memory" via chaperone modification is a potential mechanism for rapid Mallory-Denk body reinduction. Hepatology. 2008;48:931-42 pubmed publisher

product information

Product ID :

ADI-SPS-825

Catalog Number :

ADI-SPS-825-D

Product Name :

Grp75/Mortalin monoclonal antibody (30A5)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

50 µl

list of Pubmed id :

18697205

Clone :

30A5

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Mouse, Rat, Xenopus, Sheep, Rabbit, Porcine, Monkey, Hamster, Guinea pig, Drosophila, Dog, Chicken, Bovine

Background :

Grp75 (Glucose regulated 75 kDa protein) is a member of the Hsp70 family. It is localized in the mitochondrial matrix, where, in concert with Hsp60, is thought to participate in the re-folding of proteins translocated into this organelle. Like its E. coli homolog DnaK, Grp75 possesses a cation-dependent ATPase activity thought to be central to its function as a chaperone.

ALTnames :

MtHsp70, Hsp70 (mitochondrial), HspA9

Immunogen :

Native human Grp75 (Mortalin).

Buffer :

Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects a band of ~75kDa by Western blot.

Application Summary :

IHC, WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage