ERp72 (human), (recombinant) (His-tag) | Enzo Life Sciences ADI-SPP-721-200 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

ERp72 (human), (recombinant) (His-tag)

catalog :

ADI-SPP-721-200

quantity :

200 µg

product information

Product ID :

ADI-SPP-721

Catalog Number :

ADI-SPP-721-200

Product Name :

ERp72 (human), (recombinant) (His-tag)

Product Type :

Protein

Size :

200 µg

Background :

Endoplasmic reticulum protein (ERp) 72 is a member of the protein disulfide isomerase (PDI) family that is localized to the endoplasmic reticulum. It contains three repeats of the thioredoxin-like regions that is postulated to represent three independently acting catalytic domains (CGHC) of PDI activity. ERp72 contains the sequence at its carboxyl terminus which serves as its ER retention signal. Together with other ER resident proteins such as BiP, GRP94, and PDI, they serve as the molecular chaperones for proper folding of newly translocated and glycolsylated proteins such as thyroglobulin (Tg) and human chorionic gonadotropin (hCG)-b. ERp72 expression is regulated by the level of misfolding proteins in the ER, as the amount of ERp72 increased in response to epithelial ischemia, a condition that perturbs the maturation of secretory proteins.

ALTnames :

PDIA4, Protein disulfide isomerase A4

Purity :

≥85% (SDS-PAGE; Western blot)

Buffer :

Liquid. In 50mM TRIS, pH 7.5, containing 150mM sodium chloride and 1mM EDTA.

Uses :

Western blot control.

Application Summary :

WB, Activity assay

Storage :

-80°C