product summary
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company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
PDI monoclonal antibody (1D3)
catalog :
ADI-SPA-891-J
quantity :
1 mg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1D3
reactivity :
human, mouse, rat, dogs, chicken, domestic rabbit, purple urchin
application :
western blot, immunohistochemistry, immunocytochemistry, other
more info or order :
citations: 31
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:100; loading ...; fig 4b
Schrul B, Kopito R. Peroxin-dependent targeting of a lipid-droplet-destined membrane protein to ER subdomains. Nat Cell Biol. 2016;18:740-51 pubmed publisher
  • immunocytochemistry; rat
Kelly J, Shao Q, Jagger D, Laird D. Cx30 exhibits unique characteristics including a long half-life when assembled into gap junctions. J Cell Sci. 2015;128:3947-60 pubmed publisher
  • western blot; human; 1:5000; fig 1.a,b
Treacy Abarca S, Mukherjee S. Legionella suppresses the host unfolded protein response via multiple mechanisms. Nat Commun. 2015;6:7887 pubmed publisher
  • immunocytochemistry; domestic rabbit; 1:200
Hyun S, Maruri Avidal L, Moss B. Topology of Endoplasmic Reticulum-Associated Cellular and Viral Proteins Determined with Split-GFP. Traffic. 2015;16:787-95 pubmed publisher
  • immunocytochemistry; human
Takatsu H, Tanaka G, Segawa K, Suzuki J, Nagata S, Nakayama K, et al. Phospholipid flippase activities and substrate specificities of human type IV P-type ATPases localized to the plasma membrane. J Biol Chem. 2014;289:33543-56 pubmed publisher
  • western blot; human
McAlpine C, Beriault D, Behdinan T, Shi Y, Werstuck G. Oral glucosamine sulfate supplementation does not induce endoplasmic reticulum stress or activate the unfolded protein response in circulating leukocytes of human subjects. Can J Physiol Pharmacol. 2014;92:285-91 pubmed publisher
  • immunocytochemistry; mouse
Rudell J, Borges L, Rudell J, Beck K, Ferns M. Determinants in the ? and ? subunit cytoplasmic loop regulate Golgi trafficking and surface expression of the muscle acetylcholine receptor. J Biol Chem. 2014;289:203-14 pubmed publisher
  • western blot; mouse
McAlpine C, Bowes A, Khan M, Shi Y, Werstuck G. Endoplasmic reticulum stress and glycogen synthase kinase-3? activation in apolipoprotein E-deficient mouse models of accelerated atherosclerosis. Arterioscler Thromb Vasc Biol. 2012;32:82-91 pubmed publisher
  • other; human; loading ...; tbl 5.1
Hu Y, Janitz M. High-throughput subcellular protein localization using transfected-cell arrays. Subcellular protein localization using cell arrays. Methods Mol Biol. 2011;706:53-72 pubmed publisher
  • western blot; purple urchin; fig 5b
Stephens R. Ciliary protein turnover continues in the presence of inhibitors of golgi function: evidence for membrane protein pools and unconventional intracellular membrane dynamics. J Exp Zool. 2001;289:335-49 pubmed
Bolar N, Golzio C, Zivná M, Hayot G, Van Hemelrijk C, Schepers D, et al. Heterozygous Loss-of-Function SEC61A1 Mutations Cause Autosomal-Dominant Tubulo-Interstitial and Glomerulocystic Kidney Disease with Anemia. Am J Hum Genet. 2016;99:174-87 pubmed publisher
Mätlik K, Yu L, Eesmaa A, Hellman M, Lindholm P, Peränen J, et al. Role of two sequence motifs of mesencephalic astrocyte-derived neurotrophic factor in its survival-promoting activity. Cell Death Dis. 2015;6:e2032 pubmed publisher
Yaiw K, Mohammad A, Costa H, Taher C, Badrnya S, Assinger A, et al. Human Cytomegalovirus Up-Regulates Endothelin Receptor Type B: Implication for Vasculopathies?. Open Forum Infect Dis. 2015;2:ofv155 pubmed publisher
Hozumi Y, Tanaka T, Nakano T, Matsui H, Nasu T, Koike S, et al. Orotate phosphoribosyltransferase localizes to the Golgi complex and its expression levels affect the sensitivity to anti-cancer drug 5-fluorouracil. Biomed Res. 2015;36:403-9 pubmed publisher
Hernandez Valladares M, Prior I. Comparative proteomic analysis of compartmentalised Ras signalling. Sci Rep. 2015;5:17307 pubmed publisher
Capuano A, Bucciotti F, Farwell K, Tippin Davis B, Mroske C, Hulick P, et al. Diagnostic Exome Sequencing Identifies a Novel Gene, EMILIN1, Associated with Autosomal-Dominant Hereditary Connective Tissue Disease. Hum Mutat. 2016;37:84-97 pubmed publisher
Grigaravicius P, Kaminska E, Hübner C, McKinnon P, von Deimling A, Frappart P. Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain. Cell Death Differ. 2016;23:454-68 pubmed publisher
Radoshevich L, Impens F, Ribet D, Quereda J, Nam Tham T, Nahori M, et al. ISG15 counteracts Listeria monocytogenes infection. elife. 2015;4: pubmed publisher
Kato S, Chen J, Cornog K, Zhang H, Roberts J. The Golgi apparatus regulates cGMP-dependent protein kinase I compartmentation and proteolysis. Am J Physiol Cell Physiol. 2015;308:C944-58 pubmed publisher
Kentala H, Pfisterer S, Olkkonen V, Weber Boyvat M. Sterol liganding of OSBP-related proteins (ORPs) regulates the subcellular distribution of ORP-VAPA complexes and their impacts on organelle structure. Steroids. 2015;99:248-58 pubmed publisher
Avezov E, Konno T, Zyryanova A, Chen W, Laine R, Crespillo Casado A, et al. Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum. BMC Biol. 2015;13:2 pubmed publisher
Gallart Palau X, Tarabal O, Casanovas A, S bado J, Correa F, Hereu M, et al. Neuregulin-1 is concentrated in the postsynaptic subsurface cistern of C-bouton inputs to ?-motoneurons and altered during motoneuron diseases. FASEB J. 2014;28:3618-32 pubmed publisher
Tashima Y, Stanley P. Antibodies that detect O-linked ?-D-N-acetylglucosamine on the extracellular domain of cell surface glycoproteins. J Biol Chem. 2014;289:11132-42 pubmed publisher
Kornak U, Mademan I, Schinke M, Voigt M, Krawitz P, Hecht J, et al. Sensory neuropathy with bone destruction due to a mutation in the membrane-shaping atlastin GTPase 3. Brain. 2014;137:683-92 pubmed publisher
Saavedra M, Mondéjar I, Coy P, Betancourt M, González Márquez H, Jimenez Movilla M, et al. Calreticulin from suboolemmal vesicles affects membrane regulation of polyspermy. Reproduction. 2014;147:369-78 pubmed publisher
Hossain G, Lynn E, Maclean K, Zhou J, Dickhout J, Lhotak S, et al. Deficiency of TDAG51 protects against atherosclerosis by modulating apoptosis, cholesterol efflux, and peroxiredoxin-1 expression. J Am Heart Assoc. 2013;2:e000134 pubmed publisher
Takayanagi S, Fukuda R, Takeuchi Y, Tsukada S, Yoshida K. Gene regulatory network of unfolded protein response genes in endoplasmic reticulum stress. Cell Stress Chaperones. 2013;18:11-23 pubmed publisher
Bernard Marissal N, Moumen A, Sunyach C, Pellegrino C, Dudley K, Henderson C, et al. Reduced calreticulin levels link endoplasmic reticulum stress and Fas-triggered cell death in motoneurons vulnerable to ALS. J Neurosci. 2012;32:4901-12 pubmed publisher
Campbell Valois F, Trost M, Chemali M, Dill B, Laplante A, Duclos S, et al. Quantitative proteomics reveals that only a subset of the endoplasmic reticulum contributes to the phagosome. Mol Cell Proteomics. 2012;11:M111.016378 pubmed publisher
Nacev B, Grassi P, Dell A, Haslam S, Liu J. The antifungal drug itraconazole inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells. J Biol Chem. 2011;286:44045-56 pubmed publisher
Dey S, Matsunami H. Calreticulin chaperones regulate functional expression of vomeronasal type 2 pheromone receptors. Proc Natl Acad Sci U S A. 2011;108:16651-6 pubmed publisher
product information
Product ID :
ADI-SPA-891
Catalog Number :
ADI-SPA-891-J
Product Name :
PDI monoclonal antibody (1D3)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
1 mg
list of Pubmed id :
26719843, 26700594, 26620772, 26259872, 25681634, 25575667, 24803543, 24573683, 24459106, 24398873
Clone :
1D3
Isotype :
IgG1
SPECIES REACTIVITY :
Human, Mouse, Rat, Xenopus, Sheep, Rabbit, Porcine, Monkey, Hamster, Guinea pig, Dog, Chicken, Bovine
Background :
The mammalian PDI (Protein disulfide-isomerase) family encompasses several highly divergent proteins which are involved in the processing and maturation of secretory proteins in the endoplasmic reticulum by catalyzing the rearrangement of disulfide bonds.
ALTnames :
P4HB, protein disulfide isomerase
Immunogen :
Synthetic peptide corresponding to the sequence near the C-terminus of rat PDI.
Buffer :
Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Uses :
Detects a band of ~58kDa by Western blot.
Application Summary :
ICC, IF, IHC, WB, Electron microscopy
Storage :
-20°C
more info or order :
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.