Calnexin polyclonal antibody | Enzo Life Sciences ADI-SPA-865-D product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Calnexin polyclonal antibody

catalog :

ADI-SPA-865-D

quantity :

50 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, chicken, bovine, roundworm

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Enzo Life Sciences product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:2000; loading ...; fig 6f	Scheckel C, Imeri M, Schwarz P, Aguzzi A. Ribosomal profiling during prion disease uncovers progressive translational derangement in glia but not in neurons. elife. 2020;9: pubmed publisher
western blot; human; 1:1000; loading ...; fig 4a	Gerber H, Mosser S, Boury Jamot B, Stumpe M, Piersigilli A, Goepfert C, et al. The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer's disease. Acta Neuropathol Commun. 2019;7:13 pubmed publisher
western blot; human; 1:5000; loading ...; fig 2b	Chitwood P, Juszkiewicz S, Guna A, Shao S, Hegde R. EMC Is Required to Initiate Accurate Membrane Protein Topogenesis. Cell. 2018;175:1507-1519.e16 pubmed publisher
western blot; rat; loading ...; fig 1b	Blunsom N, Gomez Espinosa E, Ashlin T, Cockcroft S. Mitochondrial CDP-diacylglycerol synthase activity is due to the peripheral protein, TAMM41 and not due to the integral membrane protein, CDP-diacylglycerol synthase 1. Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863:284-298 pubmed publisher
western blot; human; 1:2000; loading ...; fig s8g	Keckesova Z, Donaher J, De Cock J, Freinkman E, Lingrell S, Bachovchin D, et al. LACTB is a tumour suppressor that modulates lipid metabolism and cell state. Nature. 2017;543:681-686 pubmed publisher
western blot; human; loading ...; fig 1b	BRANDT C, McFie P, Stone S. Diacylglycerol acyltransferase-2 and monoacylglycerol acyltransferase-2 are ubiquitinated proteins that are degraded by the 26S proteasome. Biochem J. 2016;473:3621-3637 pubmed
immunohistochemistry; human; 1:300; loading ...; fig 2d	Schrul B, Kopito R. Peroxin-dependent targeting of a lipid-droplet-destined membrane protein to ER subdomains. Nat Cell Biol. 2016;18:740-51 pubmed publisher
western blot; human; fig 3	Gerl M, Bittl V, Kirchner S, Sachsenheimer T, Brunner H, Lüchtenborg C, et al. Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions. PLoS ONE. 2016;11:e0153009 pubmed publisher
	Margaillan G, LÃ©vesque Ã, Guillemette C. Epigenetic regulation of steroid inactivating UDP-glucuronosyltransferases by microRNAs in prostate cancer. J Steroid Biochem Mol Biol. 2016;155:85-93 pubmed publisher

product information

Product ID :

ADI-SPA-865

Catalog Number :

ADI-SPA-865-D

Product Name :

Calnexin polyclonal antibody

Host species :

Rabbit

Clonality :

Polyclonal

Product Type :

Antibody

Size :

50 µg

list of Pubmed id :

26385605, 26291453, 26246218, 26113536, 26070787, 25896806, 25732993, 25587060, 25586181, 17170429

SPECIES REACTIVITY :

Human, Mouse, Rat, Xenopus, Sheep, Rabbit, Porcine, Monkey, Hamster, Guinea pig, Dog, Chicken, C. elegans, Bovine

Background :

Calnexin (CNX), an unglycosylated resident ER transmembrane protein, together with Calreticulin (CRT), plays a key role in glycoprotein folding and its control within the ER, by interacting with folding intermediates via their monoglucosylated glycans. Calnexin associates with newly synthesized monomeric glycoproteins and only recognizes glycoproteins when they are incompletely folded. Furthermore, Calnexin has been demonstrated to function as a molecular chaperone capable of interacting with polypeptide segments of folding glycoproteins.

ALTnames :

CNX

Immunogen :

Synthetic peptide corresponding to the sequence near the N-terminus of dog calnexin.

Buffer :

Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects a band of ~90kDa by Western blot.

Application Summary :

ICC, IHC (PS), IP, WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage