Calnexin polyclonal antibody | Enzo Life Sciences ADI-SPA-860-J product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Calnexin polyclonal antibody

catalog :

ADI-SPA-860-J

quantity :

1 mg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, chicken, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Enzo Life Sciences product webpage

citations: 22

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 1e	Polanco M, Parodi S, Piol D, Stack C, Chivet M, Contestabile A, et al. Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy. Sci Transl Med. 2016;8:370ra181 pubmed publisher
western blot; mouse; 1:4000; loading ...; fig 1a	Wang S, Jacquemyn J, Murru S, Martinelli P, Barth E, Langer T, et al. The Mitochondrial m-AAA Protease Prevents Demyelination and Hair Greying. PLoS Genet. 2016;12:e1006463 pubmed publisher
western blot; human; loading ...; fig 1e	Puhka M, Nordberg M, Valkonen S, Rannikko A, Kallioniemi O, Siljander P, et al. KeepEX, a simple dilution protocol for improving extracellular vesicle yields from urine. Eur J Pharm Sci. 2017;98:30-39 pubmed publisher
western blot; mouse; loading ...; fig 1a	Pigoni M, Wanngren J, Kuhn P, Munro K, Gunnersen J, Takeshima H, et al. Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons. Mol Neurodegener. 2016;11:67 pubmed
immunocytochemistry; mouse; 1:1000; fig s2a	Guo X, Sun X, Hu D, Wang Y, Fujioka H, Vyas R, et al. VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease. Nat Commun. 2016;7:12646 pubmed publisher
western blot; human; 1:2000; fig 6	Kweon H, Kim D, Bae Y, Park J, Suh B. Acid-Sensing Ion Channel 2a (ASIC2a) Promotes Surface Trafficking of ASIC2b via Heteromeric Assembly. Sci Rep. 2016;6:30684 pubmed publisher
western blot; rat; loading ...; fig 7g	Bramini M, Sacchetti S, Armirotti A, Rocchi A, Vazquez E, León Castellanos V, et al. Graphene Oxide Nanosheets Disrupt Lipid Composition, Ca(2+) Homeostasis, and Synaptic Transmission in Primary Cortical Neurons. ACS Nano. 2016;10:7154-71 pubmed publisher
western blot; chicken; 1:10,000; fig 3	Nishito Y, Tsuji N, Fujishiro H, Takeda T, Yamazaki T, Teranishi F, et al. Direct Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter. J Biol Chem. 2016;291:14773-87 pubmed publisher
western blot; mouse; loading ...; fig 9c	Sánchez A, Urrego D, Pardo L. Cyclic expression of the voltage-gated potassium channel KV10.1 promotes disassembly of the primary cilium. EMBO Rep. 2016;17:708-23 pubmed publisher
western blot; mouse; fig 2	Kuhn P, Colombo A, Schusser B, Dreymueller D, Wetzel S, Schepers U, et al. Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function. elife. 2016;5: pubmed publisher
	RYAN D, Carberry S, Murphy A, Lindner A, Fay J, Hector S, et al. Calnexin, an ER stress-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer. J Transl Med. 2016;14:196 pubmed publisher
	Schmitt D, Funk N, Blum R, Asan E, Andersen L, Rülicke T, et al. Initial characterization of a Syap1 knock-out mouse and distribution of Syap1 in mouse brain and cultured motoneurons. Histochem Cell Biol. 2016;146:489-512 pubmed publisher
	Lievens P, Kuznetsova T, Kochlamazashvili G, Cesca F, Gorinski N, Galil D, et al. ZDHHC3 Tyrosine Phosphorylation Regulates Neural Cell Adhesion Molecule Palmitoylation. Mol Cell Biol. 2016;36:2208-25 pubmed publisher
	Smagris E, Gilyard S, BasuRay S, Cohen J, Hobbs H. Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins. J Biol Chem. 2016;291:10659-76 pubmed publisher
	Di X, Wang Y, Han D, Fu Y, Duerfeldt A, Blagg B, et al. Grp94 Protein Delivers Î³-Aminobutyric Acid Type A (GABAA) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation. J Biol Chem. 2016;291:9526-39 pubmed publisher
	Salomon J, Spahn S, Wang X, FÃ¼llekrug J, Bertrand C, Mall M. Generation and functional characterization of epithelial cells with stable expression of SLC26A9 Cl- channels. Am J Physiol Lung Cell Mol Physiol. 2016;310:L593-602 pubmed publisher
	Sunkel B, Wu D, Chen Z, Wang C, Liu X, Ye Z, et al. Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence. Nucleic Acids Res. 2016;44:4105-22 pubmed publisher
	Schell C, Kretz O, Liang W, Kiefer B, Schneider S, Sellung D, et al. The Rapamycin-Sensitive Complex of Mammalian Target of Rapamycin Is Essential to Maintain Male Fertility. Am J Pathol. 2016;186:324-36 pubmed publisher
	Ulbrich L, Favaloro F, Trobiani L, Marchetti V, Patel V, Pascucci T, et al. Autism-associated R451C mutation in neuroligin3 leads to activation of the unfolded protein response in a PC12 Tet-On inducible system. Biochem J. 2016;473:423-34 pubmed publisher
	Castello R, Borzone R, D Aria S, Annunziata P, Piccolo P, Brunetti Pierri N. Helper-dependent adenoviral vectors for liver-directed gene therapy of primary hyperoxaluria type 1. Gene Ther. 2016;23:129-34 pubmed publisher
	Fleck D, Voss M, Brankatschk B, Giudici C, Hampel H, Schwenk B, et al. Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases. J Biol Chem. 2016;291:318-33 pubmed publisher
	Quadir S, Santos J, Campbell R, Wroten M, Singh N, Holloway J, et al. Homer2 regulates alcohol and stress cross-sensitization. Addict Biol. 2016;21:613-33 pubmed publisher

product information

Product ID :

ADI-SPA-860

Catalog Number :

ADI-SPA-860-J

Product Name :

Calnexin polyclonal antibody

Host species :

Rabbit

Clonality :

Polyclonal

Product Type :

Antibody

Size :

1 mg

list of Pubmed id :

26693512, 26666853, 26603938, 26574544, 26567849, 26523646, 26254965, 26070787, 25916683, 25673690

SPECIES REACTIVITY :

Human, Mouse, Rat, Xenopus, Sheep, Rabbit, Quail, Porcine, Monkey, Hamster, Guinea pig, Drosophila, Dog, Chicken, Bovine

Background :

Calnexin (CNX), an unglycosylated resident ER transmembrane protein, together with Calreticulin (CRT), plays a key role in glycoprotein folding and its control within the ER, by interacting with folding intermediates via their monoglucosylated glycans. Calnexin associates with newly synthesized monomeric glycoproteins and only recognizes glycoproteins when they are incompletely folded. Furthermore, Calnexin has been demonstrated to function as a molecular chaperone capable of interacting with polypeptide segments of folding glycoproteins.

ALTnames :

CNX

Immunogen :

Synthetic peptide corresponding to the sequence near the C-terminus of dog calnexin. The sequence is completely conserved in human, mouse and rat.

Buffer :

Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects a band of ~90kDa by Western blot.

Application Summary :

ICC, IF, IHC (PS), IP, WB, Electron microscopy

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage