HSP60 monoclonal antibody (Mab11-13) | Enzo Life Sciences ADI-SPA-829-D product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

HSP60 monoclonal antibody (Mab11-13)

catalog :

ADI-SPA-829-D

quantity :

50 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Mab-11-13

The same clone is also sold as:

Abnova: MAB16135

reactivity :

human, mouse, rat, dogs, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, other

more info or order :

Enzo Life Sciences product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:5000; fig 1a	Martínez Pizarro A, Desviat L, Ugarte M, Perez B, Richard E. Endoplasmic Reticulum Stress and Autophagy in Homocystinuria Patients with Remethylation Defects. PLoS ONE. 2016;11:e0150357 pubmed publisher
other; human; loading ...; fig st1	Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
western blot; human; fig 3	Davis A, Qiao S, Lesson J, Rojo de la Vega M, Park S, Seanez C, et al. The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells. J Biol Chem. 2015;290:1623-38 pubmed publisher

product information

Product ID :

ADI-SPA-829

Catalog Number :

ADI-SPA-829-D

Product Name :

HSP60 monoclonal antibody (Mab11-13)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

50 µg

Clone :

Mab-11-13

Isotype :

IgG2a

SPECIES REACTIVITY :

Human, Mouse, Rat, Snake, Rabbit, Porcine, Mosquito, Monkey, Hamster, Guinea pig, Fish, Drosophila, Dolphin, Dog, Bovine

Background :

Hsp60 is a member of the chaperonin family of heat shock proteins, with homologs functioning in the cytosol and mitochondria to fold nascent and aggregated proteins. Hsp60 is the eukaryotic homolog of the E. coli GroEL protein, and forms a multimeric complex in the mitochondria with Hsp10 (Cpn10) to form a large central cavity in which ATP-dependent protein folding takes place. TRiC/CCT, a eukaryotic relative of Hsp60, is expressed in the cytosol and participates in the folding of actin and tubulin substrates, but lacks any association with an Hsp10-like co-factor.

ALTnames :

Chaperonin 60, CPN60, HspD1, heat shock protein 60

Immunogen :

Recombinant human Hsp60.

Buffer :

Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects a band of ~60kDa by Western blot.

Application Summary :

FC, IF, IHC (PS), WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage