Grp78/BiP polyclonal antibody | Enzo Life Sciences ADI-SPA-826-F product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Grp78/BiP polyclonal antibody

catalog :

ADI-SPA-826-F

quantity :

200 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

Enzo Life Sciences product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; 1:1000; fig s6a	Guo X, Sun X, Hu D, Wang Y, Fujioka H, Vyas R, et al. VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease. Nat Commun. 2016;7:12646 pubmed publisher
immunoprecipitation; human; fig 3	Huang K, Chen Z, Jiang Y, Akare S, Kolber Simonds D, Condon K, et al. Apratoxin A Shows Novel Pancreas-Targeting Activity through the Binding of Sec 61. Mol Cancer Ther. 2016;15:1208-16 pubmed publisher
	Joly A, Deepti A, Seignez A, Goloudina A, Hebrard S, Schmitt E, et al. The HSP90 inhibitor, 17AAG, protects the intestinal stem cell niche and inhibits graft versus host disease development. Oncogene. 2016;35:2842-51 pubmed publisher

product information

Product ID :

ADI-SPA-826

Catalog Number :

ADI-SPA-826-F

Product Name :

Grp78/BiP polyclonal antibody

Host species :

Rabbit

Clonality :

Polyclonal

Product Type :

Antibody

Size :

200 µg

list of Pubmed id :

26422066, 26364610, 26152724, 18395818, 18266951, 17182856, 12670894, 12659845, 12584255, 11897784

SPECIES REACTIVITY :

Mouse, Rat, Xenopus, Rabbit, Monkey, Hamster, Fungus, Bovine

Background :

Grp78 (Glucose Regulated 78kDa Protein), is also known as BiP or Immunoglobulin heavy chain binding protein. It is a stressresponse protein which is induced by agents or conditions that adversely affect endoplasmic reticulum (ER) function. This protein is essential for the proper glycosylation, folding, and assembly of many membrane bound and secreted proteins as well as for maintenance of cell homeostasis and the prevention of apoptosis.

ALTnames :

HspA5, HSP70-5, Glucose-regulated protein 78, Heat shock 70kDa protein 5

Immunogen :

Synthetic peptide corresponding to the sequence near the C-terminus of rat Grp78 (BiP). The sequence is completely conserved in mouse and hamster.

Buffer :

Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects a band of ~78kDa by Western blot.

Application Summary :

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage