| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 6
| Inda M, Joshi S, Wang T, Bolaender A, Gandu S, Koren Iii J, et al. The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction. Nat Commun. 2020;11:319 pubmed publisher |
- proximity ligation assay; human; 1:100; loading ...; fig 3a
| Eftekharzadeh B, Banduseela V, Chiesa G, Martínez Cristóbal P, Rauch J, Nath S, et al. Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor. Nat Commun. 2019;10:3562 pubmed publisher |
- western blot; human; loading ...; fig 2b
| Dorsch L, Schuldt M, dos Remedios C, Schinkel A, de Jong P, Michels M, et al. Protein Quality Control Activation and Microtubule Remodeling in Hypertrophic Cardiomyopathy. Cells. 2019;8: pubmed publisher |
- immunocytochemistry; human; 1:100; loading ...; fig 6s1b
- western blot; human; 1:5000; loading ...; fig 2g, 6h, 6s1e
| Azkanaz M, Rodríguez López A, de Boer B, Huiting W, Angrand P, Vellenga E, et al. Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock. elife. 2019;8: pubmed publisher |
- western blot; human; loading ...; fig 3g
| Lee E, Ouzounova M, Piranlioglu R, Ma M, Guzel M, Marasco D, et al. The pleiotropic effects of TNFα in breast cancer subtypes is regulated by TNFAIP3/A20. Oncogene. 2019;38:469-482 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 3b
| Sevin M, Kubovcakova L, Pernet N, Causse S, Vitte F, Villeval J, et al. HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis. Nat Commun. 2018;9:1431 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 4a
| Matějů D, Franzmann T, Patel A, Kopach A, Boczek E, Maharana S, et al. An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function. EMBO J. 2017;36:1669-1687 pubmed publisher |
- western blot; human; loading ...; fig 4d
| Yentrapalli R, Merl Pham J, Azimzadeh O, Mutschelknaus L, Peters C, Hauck S, et al. Quantitative changes in the protein and miRNA cargo of plasma exosome-like vesicles after exposure to ionizing radiation. Int J Radiat Biol. 2017;93:569-580 pubmed publisher |
- western blot; chicken; fig 4
| Li Y, Ming F, Huang H, Guo K, Chen H, Jin M, et al. Proteome Response of Chicken Embryo Fibroblast Cells to Recombinant H5N1 Avian Influenza Viruses with Different Neuraminidase Stalk Lengths. Sci Rep. 2017;7:40698 pubmed publisher |
- western blot; dogs; 1:1000; loading ...; fig 3
| Graner A, Hellwinkel J, Lencioni A, Madsen H, Harland T, Marchando P, et al. HSP90 inhibitors in the context of heat shock and the unfolded protein response: effects on a primary canine pulmonary adenocarcinoma cell line. Int J Hyperthermia. 2017;33:303-317 pubmed publisher |
- western blot; human; loading ...; fig 2e
| Cumming K, Ellefsen S, Rønnestad B, Ugelstad I, Raastad T. Acute and long-term effects of blood flow restricted training on heat shock proteins and endogenous antioxidant systems. Scand J Med Sci Sports. 2017;27:1190-1201 pubmed publisher |
- western blot; human; loading ...; fig 4b
| Rodina A, Wang T, Yan P, Gomes E, Dunphy M, Pillarsetty N, et al. The epichaperome is an integrated chaperome network that facilitates tumour survival. Nature. 2016;538:397-401 pubmed publisher |
- western blot; mouse; 1:1000; fig 2
| Golovko A, Kojukhov A, Guan B, Morpurgo B, Merrick W, Mazumder B, et al. The eIF2A knockout mouse. Cell Cycle. 2016;15:3115-3120 pubmed |
- immunoprecipitation; mouse; loading ...; fig 6a
| Reeg S, Jung T, Castro J, Davies K, Henze A, Grune T. The molecular chaperone Hsp70 promotes the proteolytic removal of oxidatively damaged proteins by the proteasome. Free Radic Biol Med. 2016;99:153-166 pubmed publisher |
- western blot; human; fig 1
| Dhamad A, Zhou Z, Zhou J, Du Y. Systematic Proteomic Identification of the Heat Shock Proteins (Hsp) that Interact with Estrogen Receptor Alpha (ER?) and Biochemical Characterization of the ER?-Hsp70 Interaction. PLoS ONE. 2016;11:e0160312 pubmed publisher |
- western blot; African green monkey; 1:1000; loading ...; fig 7b
| Lee J, Takahama S, Zhang G, Tomarev S, Ye Y. Unconventional secretion of misfolded proteins promotes adaptation to proteasome dysfunction in mammalian cells. Nat Cell Biol. 2016;18:765-76 pubmed publisher |
- western blot; human; 1:4000; loading ...; fig 1
| Nilsen T, Thorsen L, Kirkegaard C, Ugelstad I, Fossa S, Raastad T. The effect of strength training on muscle cellular stress in prostate cancer patients on ADT. Endocr Connect. 2016;5:74-82 pubmed publisher |
- western blot; mouse; 1:10,000; fig 1
- immunohistochemistry - frozen section; human; 1:50; fig 7
- western blot; human; 1:10,000; fig 3
| Lin P, Folorunso O, Taglialatela G, Pierce A. Overexpression of heat shock factor 1 maintains TAR DNA binding protein 43 solubility via induction of inducible heat shock protein 70 in cultured cells. J Neurosci Res. 2016;94:671-82 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:200; fig 1
| Trieb K, Sulzbacher I, Kubista B. Recurrence rate and progression of chondrosarcoma is correlated with heat shock protein expression. Oncol Lett. 2016;11:521-524 pubmed |
- western blot; human; fig 3
| Asano Y, Kawase T, Okabe A, Tsutsumi S, Ichikawa H, Tatebe S, et al. IER5 generates a novel hypo-phosphorylated active form of HSF1 and contributes to tumorigenesis. Sci Rep. 2016;6:19174 pubmed publisher |
- western blot; human; loading ...; fig 2
| Pettersen K, Monsen V, Hakvåg Pettersen C, Overland H, Pettersen G, Samdal H, et al. DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy. Free Radic Biol Med. 2016;90:158-72 pubmed publisher |
- western blot; mouse; 1:1000; fig 5
| Larabee C, Georgescu C, Wren J, Plafker S. Expression profiling of the ubiquitin conjugating enzyme UbcM2 in murine brain reveals modest age-dependent decreases in specific neurons. BMC Neurosci. 2015;16:76 pubmed publisher |
- western blot; dogs; 1:2000; fig 5
| Clemente Vicario F, Alvarez C, ROWELL J, Roy S, London C, Kisseberth W, et al. Human Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell Lines. PLoS ONE. 2015;10:e0142007 pubmed publisher |
- western blot; mouse; 1:1000; fig 1
| Zhou J, Wan J, Gao X, Zhang X, Jaffrey S, Qian S. Dynamic m(6)A mRNA methylation directs translational control of heat shock response. Nature. 2015;526:591-4 pubmed publisher |
- western blot; human; fig 3
| Xiong R, Zhou W, Siegel D, Kitson R, Freed C, Moody C, et al. A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T α-Synuclein Toxicity. Mol Pharmacol. 2015;88:1045-54 pubmed publisher |
- western blot; human; fig 2
| Schilling D, Kühnel A, Tetzlaff F, Konrad S, Multhoff G. NZ28-induced inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. Cancer Immunol Immunother. 2015;64:599-608 pubmed publisher |
- western blot; rat; loading ...; fig 1A
| Rogers R, Beaudoin M, Wheatley J, Wright D, Geiger P. Heat shock proteins: in vivo heat treatments reveal adipose tissue depot-specific effects. J Appl Physiol (1985). 2015;118:98-106 pubmed publisher |
- western blot; human; fig 4
| Davis A, Qiao S, Lesson J, Rojo de la Vega M, Park S, Seanez C, et al. The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells. J Biol Chem. 2015;290:1623-38 pubmed publisher |
- western blot; human; 1:1000; fig 3
| Ramirez V, Krueger W, Aneskievich B. TNIP1 reduction of HSPA6 gene expression occurs in promoter regions lacking binding sites for known TNIP1-repressed transcription factors. Gene. 2015;555:430-7 pubmed publisher |
- western blot; rat; 1:1000; fig 6
| Leyk J, Goldbaum O, Noack M, Richter Landsberg C. Inhibition of HDAC6 modifies tau inclusion body formation and impairs autophagic clearance. J Mol Neurosci. 2015;55:1031-46 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 1f
| Ramirez V, Stamatis M, Shmukler A, Aneskievich B. Basal and stress-inducible expression of HSPA6 in human keratinocytes is regulated by negative and positive promoter regions. Cell Stress Chaperones. 2015;20:95-107 pubmed publisher |
- western blot; beetles ; tbl 5
| Dahlhoff E, Rank N. Functional and physiological consequences of genetic variation at phosphoglucose isomerase: heat shock protein expression is related to enzyme genotype in a montane beetle. Proc Natl Acad Sci U S A. 2000;97:10056-61 pubmed |
| Bonsergent E, Grisard E, Buchrieser J, Schwartz O, Thery C, Lavieu G. Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells. Nat Commun. 2021;12:1864 pubmed publisher |
| Schuster S, Heuten E, Velic A, Admard J, Synofzik M, Ossowski S, et al. CHIP mutations affect the heat shock response differently in human fibroblasts and iPSC-derived neurons. Dis Model Mech. 2020;13: pubmed publisher |
| Ryu S, Stewart R, Pectol D, Ender N, Wimalarathne O, Lee J, et al. Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells. PLoS Biol. 2020;18:e3000606 pubmed publisher |
| Araki K, Kawauchi K, Sugimoto W, Tsuda D, Oda H, Yoshida R, et al. Mitochondrial protein E2F3d, a distinctive E2F3 product, mediates hypoxia-induced mitophagy in cancer cells. Commun Biol. 2019;2:3 pubmed publisher |
| Lee D, Takayama S, Goldberg A. ZFAND5/ZNF216 is an activator of the 26S proteasome that stimulates overall protein degradation. Proc Natl Acad Sci U S A. 2018;115:E9550-E9559 pubmed publisher |
| Wang H, Bu L, Wang C, Zhang Y, Zhou H, Zhang X, et al. The Hsp70 inhibitor 2-phenylethynesulfonamide inhibits replication and carcinogenicity of Epstein-Barr virus by inhibiting the molecular chaperone function of Hsp70. Cell Death Dis. 2018;9:734 pubmed publisher |
| Justiniano R, Perer J, Hua A, Fazel M, Krajisnik A, Cabello C, et al. A Topical Zinc Ionophore Blocks Tumorigenic Progression in UV-exposed SKH-1 High-risk Mouse Skin. Photochem Photobiol. 2017;93:1472-1482 pubmed publisher |
| Seo J, Park J, Lee E, Vo T, Choi H, Kim J, et al. ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation. Nat Commun. 2016;7:12882 pubmed publisher |
| Xie F, Zhan R, Yan L, Gong J, Zhao Y, Ma J, et al. Diet-induced elevation of circulating HSP70 may trigger cell adhesion and promote the development of atherosclerosis in rats. Cell Stress Chaperones. 2016;21:907-14 pubmed publisher |
| Sclip A, Bacaj T, Giam L, Sudhof T. Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction. PLoS ONE. 2016;11:e0158295 pubmed publisher |
| Podgorski K, Ranganathan G. Brain heating induced by near-infrared lasers during multiphoton microscopy. J Neurophysiol. 2016;116:1012-23 pubmed publisher |
| Chooi W, Chan B. Compression loading-induced stress responses in intervertebral disc cells encapsulated in 3D collagen constructs. Sci Rep. 2016;6:26449 pubmed publisher |
| Kasza A, Hunya A, Frank Z, Fulop F, Torok Z, Balogh G, et al. Dihydropyridine Derivatives Modulate Heat Shock Responses and have a Neuroprotective Effect in a Transgenic Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2016;53:557-71 pubmed publisher |
| Lavinsky D, Wang J, Huie P, Dalal R, Lee S, Lee D, et al. Nondamaging Retinal Laser Therapy: Rationale and Applications to the Macula. Invest Ophthalmol Vis Sci. 2016;57:2488-500 pubmed publisher |
| Gutierrez E, Seebacher N, Arzuman L, Kovacevic Z, Lane D, Richardson V, et al. Lysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT). Biochim Biophys Acta. 2016;1863:1665-81 pubmed publisher |
| Andreeva N, Zatsepina O, Garbuz D, Evgen ev M, Belyavsky A. Recombinant HSP70 and mild heat shock stimulate growth of aged mesenchymal stem cells. Cell Stress Chaperones. 2016;21:727-33 pubmed publisher |
| Kim J, Son Y, Jung M, Jeong Y, Kim S, Lee S, et al. Geranylgeranylacetone alleviates radiation-induced lung injury by inhibiting epithelial-to-mesenchymal transition signaling. Mol Med Rep. 2016;13:4666-70 pubmed publisher |
| Tamura Y, Matsunaga Y, Kitaoka Y, Hatta H. Effects of Heat Stress Treatment on Age-dependent Unfolded Protein Response in Different Types of Skeletal Muscle. J Gerontol A Biol Sci Med Sci. 2017;72:299-308 pubmed publisher |
| Peppler W, Anderson Z, Sutton C, Rector R, Wright D. Voluntary wheel running attenuates lipopolysaccharide-induced liver inflammation in mice. Am J Physiol Regul Integr Comp Physiol. 2016;310:R934-42 pubmed publisher |
| Shi L, Gehin T, Chevolot Y, Souteyrand E, Mangé A, Solassol J, et al. Anti-heat shock protein autoantibody profiling in breast cancer using customized protein microarray. Anal Bioanal Chem. 2016;408:1497-506 pubmed publisher |
| Sarkar S, Leo B, Carranza C, Chen S, Rivas Santiago C, Porter A, et al. Modulation of Human Macrophage Responses to Mycobacterium tuberculosis by Silver Nanoparticles of Different Size and Surface Modification. PLoS ONE. 2015;10:e0143077 pubmed publisher |
| Kern P, Cramp R, Seebacher F, Ghanizadeh Kazerouni E, Franklin C. Plasticity of protective mechanisms only partially explains interactive effects of temperature and UVR on upper thermal limits. Comp Biochem Physiol A Mol Integr Physiol. 2015;190:75-82 pubmed publisher |
| Jiang Q, Zhang Z, Li S, Wang Z, Ma Y, Hu Y. Defective heat shock factor 1 inhibits the growth of fibrosarcoma derived from simian virus 40/T antigen‑transformed MEF cells. Mol Med Rep. 2015;12:6517-26 pubmed publisher |
| Kim J, Lee Y, Choi D, Yi H. Expression of Heat Shock Proteins (HSPs) in Aged Skeletal Muscles Depends on the Frequency and Duration of Exercise Training. J Sports Sci Med. 2015;14:347-53 pubmed |
| Tamura Y, Kitaoka Y, Matsunaga Y, Hoshino D, Hatta H. Daily heat stress treatment rescues denervation-activated mitochondrial clearance and atrophy in skeletal muscle. J Physiol. 2015;593:2707-20 pubmed publisher |
| Schilling D, Kühnel A, Konrad S, Tetzlaff F, Bayer C, Yaglom J, et al. Sensitizing tumor cells to radiation by targeting the heat shock response. Cancer Lett. 2015;360:294-301 pubmed publisher |
| Liu Y, Yu Y, Chu H, Bing D, Wang S, Zhou L, et al. 17-DMAG induces Hsp70 and protects the auditory hair cells from kanamycin ototoxicity in vitro. Neurosci Lett. 2015;588:72-7 pubmed publisher |
| Chidlow G, Wood J, Casson R. Expression of inducible heat shock proteins Hsp27 and Hsp70 in the visual pathway of rats subjected to various models of retinal ganglion cell injury. PLoS ONE. 2014;9:e114838 pubmed publisher |
| Kabbaj F, Lu S, Faouzi M, Meddah B, Proksch P, Cherrah Y, et al. Bioactive metabolites from Chaetomium aureum: structure elucidation and inhibition of the Hsp90 machine chaperoning activity. Bioorg Med Chem. 2015;23:126-31 pubmed publisher |
| Roufayel R, Johnston D, Mosser D. The elimination of miR-23a in heat-stressed cells promotes NOXA-induced cell death and is prevented by HSP70. Cell Death Dis. 2014;5:e1546 pubmed publisher |
| Dang V, Tanabe K, Tanaka Y, Tokumoto N, Misumi T, Saeki Y, et al. Fasting enhances TRAIL-mediated liver natural killer cell activity via HSP70 upregulation. PLoS ONE. 2014;9:e110748 pubmed publisher |
| Cumming K, Raastad T, Holden G, Bastani N, Schneeberger D, Paronetto M, et al. Effects of vitamin C and E supplementation on endogenous antioxidant systems and heat shock proteins in response to endurance training. Physiol Rep. 2014;2: pubmed publisher |
| Chow A, Tang D, Hanif A, Brown I. Localization of heat shock proteins in cerebral cortical cultures following induction by celastrol. Cell Stress Chaperones. 2014;19:845-51 pubmed publisher |
| Yeste M, Estrada E, Rivera Del Ãlamo M, Bonet S, Rigau T, RodrÃguez Gil J. The increase in phosphorylation levels of serine residues of protein HSP70 during holding time at 17°C is concomitant with a higher cryotolerance of boar spermatozoa. PLoS ONE. 2014;9:e90887 pubmed publisher |
| Agulla J, Brea D, Campos F, Sobrino T, Argibay B, Al Soufi W, et al. In vivo theranostics at the peri-infarct region in cerebral ischemia. Theranostics. 2013;4:90-105 pubmed publisher |
| Vydra N, Toma A, Glowala Kosinska M, Gogler Piglowska A, Widlak W. Overexpression of Heat Shock Transcription Factor 1 enhances the resistance of melanoma cells to doxorubicin and paclitaxel. BMC Cancer. 2013;13:504 pubmed publisher |
| Minguez L, Brulé N, Sohm B, Devin S, Giambérini L. Involvement of apoptosis in host-parasite interactions in the zebra mussel. PLoS ONE. 2013;8:e65822 pubmed publisher |
| Middlekauff H, Vigna C, Verity M, Fonarow G, Horwich T, Hamilton M, et al. Abnormalities of calcium handling proteins in skeletal muscle mirror those of the heart in humans with heart failure: a shared mechanism?. J Card Fail. 2012;18:724-33 pubmed publisher |
| Mitra S, Giesselman B, De Jesús Andino F, Foster T. Tumor response to mTHPC-mediated photodynamic therapy exhibits strong correlation with extracellular release of HSP70. Lasers Surg Med. 2011;43:632-43 pubmed publisher |
| Needham P, Mikoluk K, Dhakarwal P, Khadem S, Snyder A, Subramanya A, et al. The thiazide-sensitive NaCl cotransporter is targeted for chaperone-dependent endoplasmic reticulum-associated degradation. J Biol Chem. 2011;286:43611-21 pubmed publisher |
| Shorter J. The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system. PLoS ONE. 2011;6:e26319 pubmed publisher |
