HSP40/Hdj1 polyclonal antibody | Enzo Life Sciences ADI-SPA-400-D product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

HSP40/Hdj1 polyclonal antibody

catalog :

ADI-SPA-400-D

quantity :

50 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, chicken, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, proximity ligation assay

more info or order :

Enzo Life Sciences product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
proximity ligation assay; human; 1:100; loading ...; fig 3c western blot; rat; loading ...; fig 5c	Eftekharzadeh B, Banduseela V, Chiesa G, Martínez Cristóbal P, Rauch J, Nath S, et al. Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor. Nat Commun. 2019;10:3562 pubmed publisher
	Asano Y, Kawase T, Okabe A, Tsutsumi S, Ichikawa H, Tatebe S, et al. IER5 generates a novel hypo-phosphorylated active form of HSF1 and contributes to tumorigenesis. Sci Rep. 2016;6:19174 pubmed publisher

product information

Product ID :

ADI-SPA-400

Catalog Number :

ADI-SPA-400-D

Product Name :

HSP40/Hdj1 polyclonal antibody

Host species :

Rabbit

Clonality :

Polyclonal

Product Type :

Antibody

Size :

50 µg

list of Pubmed id :

26060190, 22768276, 18945763, 18775310, 17441507, 17012257, 12364339, 12213295, 11875046, 11406612

SPECIES REACTIVITY :

Human, Mouse, Rat, Xenopus, Sheep, Scallop, Rabbit, Porcine, Mussel, Monkey, Hamster, Guinea pig, Fish, Dog, Chicken, Bovine, Beluga

Background :

Hsp40/Hdj1 is a cytosolic co-chaperone belonging to the class DnaJ, named after its homolog in E. coli. Hsp40 functions in protein folding by binding nascent peptides and unfolded substrates and facilitating substrate interaction with Hsp70. Binding of Hsp40 to Hsp70 increases Hsp70 ATP hydrolysis and substrate binding, which is reversed by the action of nucleotide exchange factors (GrpE in E. coli). Repeated cycles of Hsp40/Hsp70 peptide binding and ATP hydrolysis prevent premature folding and aggregation, promoting protein maturation throughout the cell.

ALTnames :

Heat shock protein 40

Immunogen :

Recombinant human Hsp40.

Buffer :

Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects a band of ~40kDa by Western blot.

Application Summary :

ICC, IF, IHC (PS), IP, WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage