β-Crystallin monoclonal antibody (3.H9.2) | Enzo Life Sciences ADI-SPA-230-F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

β-Crystallin monoclonal antibody (3.H9.2)

catalog :

ADI-SPA-230-F

quantity :

200 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3.H9.2

application :

western blot

citations: 1

Reference
Suzuki T, Bando M, Oka M, Tsukamoto H, Akatsuka I, Kawai K, et al. lambda-crystallin related to dehydroascorbate reductase in the rabbit lens. Jpn J Ophthalmol. 2003;47:437-43 pubmed

product information

Product ID :

ADI-SPA-230

Catalog Number :

ADI-SPA-230-F

Product Name :

β-Crystallin monoclonal antibody (3.H9.2)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

200 µg

list of Pubmed id :

12967857

Clone :

3.H9.2

Isotype :

IgG1

SPECIES REACTIVITY :

Rabbit, Bovine

Background :

The beta-crystallins comprise a complex group of heteropolymers which are assembled from 6 primary gene products, the acidic (betaA1, betaA2, betaA3) and the basic (betaB1, betaB2, betaB3) polypeptides. beta-crystallins generally represent the second most abundant group of proteins in the lens but their proportions and properties vary with development. In the prenatal bovine lens, beta-crystallins account for 30% of the total proteins and betaH is predominant. In the adult, the total has increased to 40% due to an increased production of the betaL species. With the exception of betaB1a and betaB1b which are found only in betaH and appear to be responsible for its aggregation, all polypeptides are found in all forms of the protein. The betaB2 polypeptide (previously called betaBp) predominates, accounting for about 50% of the total. The lack of stoichiometry in the subunit contents suggests that each of the different molecular weight populations is a mixture of aggregates with most of the major polypeptides represented. These various species appear to be in equilibrium and their proportions vary with protein concentration. It is likely that even more highly aggregated forms, are the major species in the lens.

ALTnames :

CRYBB

Immunogen :

Native bovine β-crystallin.

Buffer :

Liquid. In PBS containing 0.09% sodium azide and 50% glycerol.

Uses :

Detects a band of ~25kDa by Western blot.

Application Summary :

Storage :

-20°C