Cu/Zn SOD polyclonal antibody (biotin conjugate) | Enzo Life Sciences ADI-SOD-100B-0200 product information

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product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Cu/Zn SOD polyclonal antibody (biotin conjugate)

catalog :

ADI-SOD-100B-0200

quantity :

200 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

biotin

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 6

Reference
Delp M, Charvat J, Limoli C, Globus R, Ghosh P. Apollo Lunar Astronauts Show Higher Cardiovascular Disease Mortality: Possible Deep Space Radiation Effects on the Vascular Endothelium. Sci Rep. 2016;6:29901 pubmed publisher
Horváthová F, Danielisova V, Domoráková I, Solar P, Rybarova S, Hodorová I, et al. The effect of R-(-)-deprenyl administration on antioxidant enzymes in rat testis. Eur J Pharmacol. 2016;788:21-28 pubmed publisher
Ghosh P, Behnke B, Stabley J, Kilar C, Park Y, Narayanan A, et al. Effects of High-LET Radiation Exposure and Hindlimb Unloading on Skeletal Muscle Resistance Artery Vasomotor Properties and Cancellous Bone Microarchitecture in Mice. Radiat Res. 2016;185:257-66 pubmed publisher
Shelar S, Narasimhan M, Shanmugam G, Litovsky S, Gounder S, Karan G, et al. Disruption of nuclear factor (erythroid-derived-2)-like 2 antioxidant signaling: a mechanism for impaired activation of stem cells and delayed regeneration of skeletal muscle. FASEB J. 2016;30:1865-79 pubmed publisher
McCormick R, Pearson T, Vasilaki A. Manipulation of environmental oxygen modifies reactive oxygen and nitrogen species generation during myogenesis. Redox Biol. 2016;8:243-51 pubmed publisher
LefÃ¨vre P, Berger R, Ernest S, Gaertner D, Rawn D, Wade M, et al. Exposure of Female Rats to an Environmentally Relevant Mixture of Brominated Flame Retardants Targets the Ovary, Affecting Folliculogenesis and Steroidogenesis. Biol Reprod. 2016;94:9 pubmed publisher

product information

Product ID :

ADI-SOD-100B

Catalog Number :

ADI-SOD-100B-0200

Product Name :

Cu/Zn SOD polyclonal antibody (biotin conjugate)

Host species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Biotin

Product Type :

Antibody

Size :

200 µg

SPECIES REACTIVITY :

Human, Mouse, Rat, Clam

Background :

Superoxide dismutase (SOD) is responsible for the elimination of cytotoxic active oxygen by catalyzing the dismutation of the superoxide radical to oxygen and hydrogen peroxide. There are three SOD isoenzymes in mammalian cells: extracellular SOD (EC SOD, SOD-3); copper and zinc-containing SOD (Cu/Zn SOD, SOD-1); and manganese-containing SOD (Mn SOD, SOD-2). The Cu/Zn form binds Cu and Zn ions and exists as a soluble 32kDa homodimer in the cytosol. Mutations in the SOD-1 gene accounts for approximately 20% of amyelotrophic lateral sclerosis (ALS) or ‘Lou Gehrig disease,’ a neurodegenerative disorder characterized by the death of motor neurons in the brain, brainstem, and spinal cord that results in fatal paralysis.

ALTnames :

Superoxide Dismutase (Cu-Zn), Superoxide dismutase 1, SOD1

Immunogen :

Native human Cu/Zn SOD.

Buffer :

Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects a band of ~23kDa (human) or ~19kDa (mouse and rat) by Western blot.

Application Summary :

IF, IHC (PS), IP, WB

Storage :

-20°C