Erk1 (human), (recombinant) | Enzo Life Sciences ADI-PPK-420-Z product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

Erk1 (human), (recombinant)

catalog :

ADI-PPK-420-Z

quantity :

5 µg

product information

Product ID :

ADI-PPK-420

Catalog Number :

ADI-PPK-420-Z

Product Name :

Erk1 (human), (recombinant)

Product Type :

Protein

Size :

5 µg

Background :

ERK1 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines. Activation of ERK1 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK1 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. In vitro studies indicate that ERK1 phosphorylate both nuclear and cytoplasmic proteins. Activated ERK1 translocates into the nucleus where it phosphorylates various transcription factors (e.g., Elk-1, c- Myc, c-Jun, c-Fos, and C/EBP beta). The consensus primary sequence for substrate phosphorylation by ERK1 has been identified as -Pro-Leu-Ser/Thr-Pro-. ERK1 has been implicated in the control of a broad spectrum of cellular events in many types of cells. In somatic cells, ERK1 activation seems to be triggered after exit from a quiescent state (in G0 or G2) only and then inactivated by entry into a proliferative state.

ALTnames :

MAPK3, MAP kinase 3

Purity :

≥80% (SDS-PAGE)

Buffer :

Liquid. In 50mM TRIS-hydrogen chloride, pH 7.5, containing 150mM sodium chloride, 0.25mM DTT, 0.1mM EGTA, and 30% glycerol.

Application Summary :

Kinase assay

Storage :

-80°C