product summary
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company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Cysteine (sulfonate) polyclonal antibody
catalog :
ADI-OSA-820-D
quantity :
50 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot
more info or order :
Enzo Life Sciences product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 5a
Huang C, Huang Y, Shen Z, Lin C, Tsai T. Cisd2 Preserves the Youthful Pattern of the Liver Proteome during Natural Aging of Mice. Biomedicines. 2021;9: pubmed publisher
product information
Product ID :
ADI-OSA-820
Catalog Number :
ADI-OSA-820-D
Product Name :
Cysteine (sulfonate) polyclonal antibody
Host species :
Rabbit
Clonality :
Polyclonal
Product Type :
Antibody
Size :
50 µg
list of Pubmed id :
19805274
Product Description :
This antibody detects sulfenic, sulfonic and sulfinic acid modified proteins.
SPECIES REACTIVITY :
Human
Background :
Reduction and oxidation (redox) play a critical role in a wide variety of biological processes including respiration, photosynthesis, proteostasis, and cell stress, among others. Redox signaling is accomplished by networks of regulatory enzymes and proteins which modulate the oxidative state of biological molecules, with cysteine thiol side chains playing a critical role. The highly nucleophilic and polarizable sulfur atom can occupy sulfenic (RSOH), sulfinic (RSO2H) or sulfonic (RSO3H) states. Within a protein body, the various redox forms of cysteine can be transiently stabilized and play an active role in regulating or altering protein activity or absorbing oxidative stress. The ability to stabilize and quantify these oxidative forms allows analysis of redox regulation at a level of detail which transcends traditional methods that quantify protein or free radicals. Chemical modification can be utilized to stabilize these transient oxidative forms for subsequent detection, and has been successfully employed in the detection of the sulfenic acid form.
Immunogen :
Recombinant human cysteine (sulfonate). Cysteamine backbone modified by dimedone with a five-carbon linker to KLH.
Specificity :
Recognizes all forms of cysteine with an oxidized thiol group (sulfenic RSOH, sulfinic RSO2H and sulfonic RSO3H).
Buffer :
Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Application Summary :
WB
Storage :
-20°C
more info or order :
Enzo Life Sciences product webpage
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.