product summary
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company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
PDK1 polyclonal antibody
catalog :
ADI-KAP-PK112-F
quantity :
200 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
more info or order :
citations: 4
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 3
Lim S, Liu H, Madeira da Silva L, Arora R, Liu Z, Phillips J, et al. Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1?. Cancer Res. 2016;76:2231-42 pubmed publisher
Karner C, Esen E, Chen J, Hsu F, Turk J, Long F. Wnt Protein Signaling Reduces Nuclear Acetyl-CoA Levels to Suppress Gene Expression during Osteoblast Differentiation. J Biol Chem. 2016;291:13028-39 pubmed publisher
Meiser J, Krämer L, Sapcariu S, Battello N, Ghelfi J, d Herouël A, et al. Pro-inflammatory Macrophages Sustain Pyruvate Oxidation through Pyruvate Dehydrogenase for the Synthesis of Itaconate and to Enable Cytokine Expression. J Biol Chem. 2016;291:3932-46 pubmed publisher
Valbuena G, Rizzardini M, Cimini S, Siskos A, Bendotti C, Cantoni L, et al. Metabolomic Analysis Reveals Increased Aerobic Glycolysis and Amino Acid Deficit in a Cellular Model of Amyotrophic Lateral Sclerosis. Mol Neurobiol. 2016;53:2222-40 pubmed publisher
product information
Product ID :
ADI-KAP-PK112
Catalog Number :
ADI-KAP-PK112-F
Product Name :
PDK1 polyclonal antibody
Host species :
Rabbit
Clonality :
Polyclonal
Product Type :
Antibody
Size :
200 µg
list of Pubmed id :
26514431, 25963727, 19056893, 11790708
SPECIES REACTIVITY :
Human, Mouse, Rat, Rabbit, Porcine, Monkey, Dog
Background :
PDK-1 (Pyruvate dehydrogenase kinase-1) is a 48 kDa protein kinase. It is a member of the mitrochondrial matrix protein kinase family and is related to the histidine protein kinases found in prokaryotes. PDK-1 is responsible for phosphorylation and concomitant inactivation of pyruvate dehydrogenase.
ALTnames :
Pyruvate dehydrogenase kinase
Immunogen :
Synthetic peptide corresponding to a portion of human PDK1 (Pyruvate dehydrogenase kinase-1).
Buffer :
Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Uses :
Detects a band of ~48kDa by Western blot.
Application Summary :
IHC (PS), WB
Storage :
-20°C
more info or order :
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.