PKG polyclonal antibody | Enzo Life Sciences ADI-KAP-PK002-D product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

PKG polyclonal antibody

catalog :

ADI-KAP-PK002-D

quantity :

50 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Enzo Life Sciences product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; fig 3b	Martín Sánchez P, Luengo A, Griera M, Orea M, López Olañeta M, Chiloeches A, et al. H- ras deletion protects against angiotensin II-induced arterial hypertension and cardiac remodeling through protein kinase G-Iβ pathway activation. FASEB J. 2018;32:920-934 pubmed publisher
	Prysyazhna O, Burgoyne J, Scotcher J, Grover S, Kass D, Eaton P. Phosphodiesterase 5 Inhibition Limits Doxorubicin-induced Heart Failure by Attenuating Protein Kinase G I? Oxidation. J Biol Chem. 2016;291:17427-36 pubmed publisher
	Agyeman A, Jun W, Proia D, Kim C, Skor M, Kocherginsky M, et al. Hsp90 Inhibition Results in Glucocorticoid Receptor Degradation in Association with Increased Sensitivity to Paclitaxel in Triple-Negative Breast Cancer. Horm Cancer. 2016;7:114-26 pubmed publisher
	Monsivais D, Dyson M, Yin P, Navarro A, Coon J, Pavone M, et al. Estrogen receptor Î² regulates endometriotic cell survival through serum and glucocorticoid-regulated kinase activation. Fertil Steril. 2016;105:1266-1273 pubmed publisher

product information

Product ID :

ADI-KAP-PK002

Catalog Number :

ADI-KAP-PK002-D

Product Name :

PKG polyclonal antibody

Host species :

Rabbit

Clonality :

Polyclonal

Product Type :

Antibody

Size :

50 µg

list of Pubmed id :

14512447, 12359308, 10910034

SPECIES REACTIVITY :

Human, Mouse, Rat, Bovine

Background :

Cyclic GMP-dependent protein kinases (PKGs or cGKs) are classified into two types, PKGI and PKGII. Studies have shown that PKGs are highly homologous to PKAs; phosphorylation of cellular proteins by both families of kinases leads to alterations in calcium mobilization, protein phosphatase activity, ion channel function, gene transcription, smooth muscle contractility, and platelet aggregation.

ALTnames :

Protein kinase G

Immunogen :

Synthetic peptide corresponding to a portion of human PKG1β, with the subsitiution of a tryptophan residue for tyrosine at residue 9.

Buffer :

Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects a band of ~80kDa by Western blot.

Application Summary :

ICC, IHC, IP, WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage