This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
[pSer32/Ser36]IκBα monoclonal antibody (39A1413)
catalog :
ADI-KAM-TF140-E
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
39A1413

The same clone is also sold as:
reactivity :
human, mouse, rat, dogs, bovine
application :
western blot, immunoprecipitation
product information
Product ID :
ADI-KAM-TF140
Catalog Number :
ADI-KAM-TF140-E
Product Name :
[pSer32/Ser36]IκBα monoclonal antibody (39A1413)
Host species :
Mouse
Clonality :
Monoclonal
Antigen modification :
Phosphorylated
Product Type :
Antibody
Size :
100 µg
Clone :
39A1413
Isotype :
IgG1κ
SPECIES REACTIVITY :
Human, Mouse, Rat, Porcine, Dog, Bovine
Background :
NF-κB is silenced in the cytoplasm by the inhibitory protein IkappaBa, which masks nuclear localization signals on NF-κB. IkappaBa is phosphorylated by the IkappaB kinase (IKK) complex in response to external stimuli such as tumor necrosis factor or other cytokines. IKK specifically phosphorylates IkappaBa on Ser32 and Ser36, leading to ubiquitination of IkappaBa and subsequent degradation by the 26S proteasome. Degradation of IkappaBa exposes the nuclear localization signal of NF-κB dimers, which then translocate to the nucleus to activate target genes
Immunogen :
Synthetic peptide corresponding to a portion of human IκBα phosphorylated at Ser32/36.
Buffer :
Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide.
Uses :
Detects a band of ~42kDa by Western blot.
Application Summary :
IP, WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.