[pSer780]Rb monoclonal antibody (2C4) | Enzo Life Sciences ADI-KAM-CP121-E product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

[pSer780]Rb monoclonal antibody (2C4)

catalog :

ADI-KAM-CP121-E

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

2C4

reactivity :

human

application :

western blot

citations: 1

Reference
Schertzer M, Jouravleva K, Perderiset M, Dingli F, Loew D, Le Guen T, et al. Human regulator of telomere elongation helicase 1 (RTEL1) is required for the nuclear and cytoplasmic trafficking of pre-U2 RNA. Nucleic Acids Res. 2015;43:1834-47 pubmed publisher

product information

Product ID :

ADI-KAM-CP121

Catalog Number :

ADI-KAM-CP121-E

Product Name :

[pSer780]Rb monoclonal antibody (2C4)

Host species :

Mouse

Clonality :

Monoclonal

Antigen modification :

Phosphorylated

Product Type :

Antibody

Size :

100 µg

Clone :

2C4

Isotype :

IgG1

SPECIES REACTIVITY :

Human

Background :

The Retinoblastoma (Rb) is a tumor suppressor phosphoprotein that plays a critical role in the regulation of the cell cycle. In the absence of mitogenic signaling, Rb sequesters the transcription factor E2F within the cytosol. Upon phosphorylation, E2F is liberated from Rb and translocates to the nucleus where the latter facilitates gene transcription. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

ALTnames :

Retinoblastoma-associated protein

Immunogen :

Synthetic peptide corresponding to a portion of human Rb phosphorylated at Ser780.

Buffer :

Lyophilized. In PBS, pH 7.2, containing 1% sucrose. No preservatives. For a stock solution of 1.0mg/ml reconstitute with 100μl of sterile distilled water.

Application Summary :

Storage :

-20°C