This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
ORC2 monoclonal antibody (3B7)
catalog :
ADI-KAM-CC235-E
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3B7
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 1
Reference
Kim B, Lee H. Caspase-mediated cleavage of importin-alpha increases its affinity for MCM and downregulates DNA synthesis by interrupting the binding of MCM to chromatin. Biochim Biophys Acta. 2008;1783:2287-93 pubmed publisher
product information
Product ID :
ADI-KAM-CC235
Catalog Number :
ADI-KAM-CC235-E
Product Name :
ORC2 monoclonal antibody (3B7)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
18761040
Clone :
3B7
Isotype :
IgG1
SPECIES REACTIVITY :
Human
Background :
DNA replication in Saccharomyces cerevisiae initiates from specific DNA sequences called autonomous replication sequences (ARSs), many of which have proven to be chromosomal origins of replication. The six subunit origin recognition complex (ORC) was identified initially by its ARSs binding activity in an ATP-dependent manner. ORC functions as a recruiter of cofactors such as Mcms to origins, and may also play a role in transcriptional silencing. ORC2 is the second largest subunit of the ORC but its specific function in eukaryotic cells remains unclear. In yeast, ORC2 is involved in suppression of late origins.
ALTnames :
Origin recognition complex subunit 2
Immunogen :
Recombinant human ORC2.
Buffer :
Liquid. In PBS containing 50% glycerol.
Uses :
Detects a band of ~67kDa by Western blot.
Application Summary :
ICC, IP, WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.