This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Cyclin B1 monoclonal antibody (V63)
catalog :
ADI-KAM-CC195-C
quantity :
25 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
V63
reactivity :
human, rat, dogs
application :
western blot, immunohistochemistry
citations: 1
Reference
Cahn M, Brown A, Clotfelter E. Guanine-based structural coloration as an indicator of oxidative stress in a cichlid fish. J Exp Zool A Ecol Genet Physiol. 2015;323:359-67 pubmed publisher
product information
Product ID :
ADI-KAM-CC195
Catalog Number :
ADI-KAM-CC195-C
Product Name :
Cyclin B1 monoclonal antibody (V63)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
25 µg
Clone :
V63
Isotype :
IgG1
SPECIES REACTIVITY :
Human, Mouse, Rat, Sheep, Rabbit, Porcine, Hamster, Guinea pig, Dog
Background :
In mammals, cyclin B associates with inactive p34cdc2 which facilitates phosphorylation of p34cdc2 at aa 14-Thr and 15-Tyr. This maintains the inactive state until the end of G2-phase. The inactive cyclin B-p34cdc2 complex continues to accumulate in the cytoplasm until the completion of DNA synthesis, when Cdc25, a specific protein phosphatase, dephosphorylates aa 14-Thr and 15-Tyr of p34cdc2 rendering the complex active at the G2/Mboundary. This mitotic kinase complex remains active until the metaphase/anaphase transition when cyclin B is degraded. This degradation process is ubiquitin-dependent and is necessary for the cell to exit mitosis. Therefore cyclin B-p34cdc2 plays a critical role in G2 to M transition.
ALTnames :
CCNB1
Immunogen :
Synthetic peptide corresponding to the sequence near the carboxy terminus of hamster cyclin B1.
Buffer :
Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Uses :
Detects a band of ~58kDa by Western blot.
Application Summary :
IHC, WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.