p53 monoclonal antibody (PAb122) | Enzo Life Sciences ADI-KAM-CC002-F product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

p53 monoclonal antibody (PAb122)

catalog :

ADI-KAM-CC002-F

quantity :

200 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

Pab122

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 3

Reference
Logsdon G, Barrey E, Bassett E, Denizio J, Guo L, Panchenko T, et al. Both tails and the centromere targeting domain of CENP-A are required for centromere establishment. J Cell Biol. 2015;208:521-31 pubmed publisher
Noguchi A, Kikuchi K, Ohtsu T, Yoshiwara M, Nakamura Y, Miyagi Y, et al. Pulmonary tumors associated with the JC virus T-antigen in a transgenic mouse model. Oncol Rep. 2013;30:2603-8 pubmed publisher
Jara M, Esponda P, Carballada R. Abdominal temperature induces region-specific p53-independent apoptosis in the cauda epididymidis of the mouse. Biol Reprod. 2002;67:1189-96 pubmed

product information

Product ID :

ADI-KAM-CC002

Catalog Number :

ADI-KAM-CC002-F

Product Name :

p53 monoclonal antibody (PAb122)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

200 µg

list of Pubmed id :

24100939, 12297535

Clone :

pAb122

Isotype :

IgG2b

SPECIES REACTIVITY :

Human, Mouse, Rat

Background :

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to Mdm2, SV40 T antigen and human Papilloma virus E6 protein. p53 senses DNA damage and facilitates its repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovary, bladder, colon, lung, and melanoma.

ALTnames :

TRP53, Tumor protein p53

Immunogen :

SV40 transformed 3T3 cells.

Buffer :

Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects a band of ~48/53kDa by Western blot.

Application Summary :

FC, ICC, IHC, IP, WB

Storage :

-20°C