HSP70B’ ELISA kit | Enzo Life Sciences ADI-EKS-725A product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

ELISA/assay

product name :

HSP70B’ ELISA kit

catalog :

ADI-EKS-725A

quantity :

96 wells

product information

Product ID :

ADI-EKS-725A

Catalog Number :

ADI-EKS-725A

Product Name :

HSP70B’ ELISA kit

Product Type :

Kit

Size :

96 wells

Product Description :

The HSP70B’ EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in < 4.5 hours. Absorbance is read at 450 nm. Save time, money, and precious sample with fully quantitative results and increased sensitivity compared to Western blot analysis.

SPECIES REACTIVITY :

Human

Background :

The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

ALTnames :

Heat shock protein 70, HSP72

Uses :

For the quantitative determination of HSP70B' in cell lysates, serum, and tissue of human origin.

Application Summary :

ELISA, Colorimetric detection