HSP70 high sensitivity ELISA kit | Enzo Life Sciences ADI-EKS-715 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

ELISA/assay

product name :

HSP70 high sensitivity ELISA kit

catalog :

ADI-EKS-715

quantity :

96 wells

citations: 19

Reference
Sevin M, Kubovcakova L, Pernet N, Causse S, Vitte F, Villeval J, et al. HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis. Nat Commun. 2018;9:1431 pubmed publisher
GaloviÄ‡ R, Flegar MeÅ¡triÄ‡ Z, Vidjak V, MatokanoviÄ‡ M, BariÅ¡iÄ‡ K. Heat shock protein 70 and antibodies to heat shock protein 60 are associated with cerebrovascular atherosclerosis. Clin Biochem. 2016;49:66-9 pubmed publisher
Tsai T, Lee T, Liu M, Chuang I, Lu M, Dong H, et al. Release of endogenous heat shock protein 72 on the survival of sepsis in rats. J Surg Res. 2015;198:165-74 pubmed publisher
Guisasola M, Ortiz A, Chana F, Alonso B, Vaquero J. Early inflammatory response in polytraumatized patients: Cytokines and heat shock proteins. A pilot study. Orthop Traumatol Surg Res. 2015;101:607-11 pubmed publisher
Ersvaer E, Brenner A, VetÃ¥s K, Reikvam H, Bruserud Ã. Effects of cytarabine on activation of human T cells - cytarabine has concentration-dependent effects that are modulated both by valproic acid and all-trans retinoic acid. BMC Pharmacol Toxicol. 2015;16:12 pubmed publisher
Thuringer D, Berthenet K, Cronier L, Jego G, Solary E, Garrido C. Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells. Oncotarget. 2015;6:10267-83 pubmed
Najafizadeh S, Ghazizadeh Z, Nargesi A, Mahdavi M, Abtahi S, Mirmiranpour H, et al. Analysis of serum heat shock protein 70 (HSPA1A) concentrations for diagnosis and disease activity monitoring in patients with rheumatoid arthritis. Cell Stress Chaperones. 2015;20:537-43 pubmed publisher
Cui X, Xing J, Liu Y, Zhou Y, Luo X, Zhang Z, et al. COPD and levels of Hsp70 (HSPA1A) and Hsp27 (HSPB1) in plasma and lymphocytes among coal workers: a case-control study. Cell Stress Chaperones. 2015;20:473-81 pubmed publisher
Morales Buenrostro L, Salas Nolasco O, Barrera Chimal J, Casas Aparicio G, Irizar Santana S, Pérez Villalva R, et al. Hsp72 is a novel biomarker to predict acute kidney injury in critically ill patients. PLoS ONE. 2014;9:e109407 pubmed publisher
Gomez Choco M, Doucerain C, Urra X, Planas A, Chamorro A. Presence of heat shock protein 70 in secondary lymphoid tissue correlates with stroke prognosis. J Neuroimmunol. 2014;270:67-74 pubmed publisher
Ramirez Sandoval J, Barrera Chimal J, Simancas P, Rojas Montaño A, Correa Rotter R, Bobadilla N, et al. Urinary neutrophil gelatinase-associated lipocalin predicts graft loss after acute kidney injury in kidney transplant. Biomarkers. 2014;19:63-9 pubmed publisher
Cox S, Speaker K, Beninson L, Craig W, Paton M, Fleshner M. Adrenergic and glucocorticoid modulation of the sterile inflammatory response. Brain Behav Immun. 2014;36:183-92 pubmed publisher
Shanely R, Nieman D, Zwetsloot K, Knab A, Imagita H, Luo B, et al. Evaluation of Rhodiola rosea supplementation on skeletal muscle damage and inflammation in runners following a competitive marathon. Brain Behav Immun. 2014;39:204-10 pubmed publisher
Kornej J, Reinhardt C, Kosiuk J, Arya A, Hindricks G, Adams V, et al. Response of circulating heat shock protein 70 and anti-heat shock protein 70 antibodies to catheter ablation of atrial fibrillation. J Transl Med. 2013;11:49 pubmed publisher
Lennikov A, Kitaichi N, Kase S, Noda K, Horie Y, Nakai A, et al. Induction of heat shock protein 70 ameliorates ultraviolet-induced photokeratitis in mice. Int J Mol Sci. 2013;14:2175-89 pubmed publisher
Sánchez Pozos K, Barrera Chimal J, Garzon Muvdi J, Pérez Villalva R, Rodríguez Romo R, Cruz C, et al. Recovery from ischemic acute kidney injury by spironolactone administration. Nephrol Dial Transplant. 2012;27:3160-9 pubmed publisher
Hu Y, Yeh H, Tsao H, Tai C, Lin Y, Chang S, et al. Electrophysiological correlation and prognostic impact of heat shock protein 27 in atrial fibrillation. Circ Arrhythm Electrophysiol. 2012;5:334-40 pubmed publisher
Ogawa K, Kim H, Shimizu T, Abe S, Shiga Y, Calderwood S. Plasma heat shock protein 72 as a biomarker of sarcopenia in elderly people. Cell Stress Chaperones. 2012;17:349-59 pubmed publisher
Multhoff G, Hightower L. Distinguishing integral and receptor-bound heat shock protein 70 (Hsp70) on the cell surface by Hsp70-specific antibodies. Cell Stress Chaperones. 2011;16:251-5 pubmed publisher

product information

Product ID :

ADI-EKS-715

Catalog Number :

ADI-EKS-715

Product Name :

HSP70 high sensitivity ELISA kit

Product Type :

Kit

Size :

96 wells

list of Pubmed id :

26500006, 26073348, 26068807, 25934555, 25739548, 25620081, 24656941, 24325180, 24321216, 24055627

Product Description :

The HSP70 high sensitivity EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 4.5 hours. Absorbance is read at 450 nm. This is the only commercially available kit specifically validated and sensitive enough to quantify HSP70 (HSP72) in serum and plasma samples, as referenced by the Cell Stress Society International.

SPECIES REACTIVITY :

Human, Mouse, Rat

Background :

The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

ALTnames :

Heat shock protein 70, HSP72

Uses :

For the quantitative determination of HSP70 in serum and plasma of human, mouse, and rat origin. Cited sample(s) include cell lysates and urine.

Application Summary :

ELISA, Colorimetric detection