TNF-α monoclonal antibody (1) | Enzo Life Sciences ADI-CSA-806-E product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

TNF-α monoclonal antibody (1)

catalog :

ADI-CSA-806-E

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

reactivity :

human

product information

Product ID :

ADI-CSA-806

Catalog Number :

ADI-CSA-806-E

Product Name :

TNF-α monoclonal antibody (1)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

Clone :

Isotype :

IgG1

SPECIES REACTIVITY :

Human

Background :

Tumor necrosis factor alpha (TNFalpha), also known as cachectin, is a 17.5 kDa 157 amino acid member of the TNF superfamily of cytokines that is a potent lymphoid factor with effects on a wide range of target cells. Active TNFalpha is produced in both soluble and membrane-anchored trimers by macrophages, NK cells, and T- and B-lymphocytes. TNF exerts proinflammatory signals via binding and inducing trimerization of TNF-receptor1 (TNF-R1) expressed on most normal and transformed cells, or to TNF-receptor 2 (TNF-R2), expressed on endothelial and most immune cells. TNF signaling regulates hematopeiesis, differentation, endothelial cell activation, apoptosis, lipid metabolism, tumor progression, and immune suveillance, and dysregulation of TNF or its receptors is implicated in numerous disease states including cancer, osteoporosis, autoimmune disease, diabetes, and atherosclerosis.

ALTnames :

TNFSF 2, Tumor necrosis factor-α

Immunogen :

Human TNF-α.

Buffer :

Liquid. In PBS containing 50% glycerol.

Application Summary :

FUNC

Storage :

-20°C