ARF1 monoclonal antibody (ARFS 3F1) | Enzo Life Sciences ADI-CSA-450-D product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

ARF1 monoclonal antibody (ARFS 3F1)

catalog :

ADI-CSA-450-D

quantity :

50 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ARFS 3F1

The same clone is also sold as:

Santa Cruz Biotechnology: sc-53167
Abcam: ab11038

reactivity :

human, mouse, rat, dogs, chicken

application :

western blot

citations: 1

Reference
Zhou F, Dong C, Davis J, Wu W, Surrao K, Wu G. The mechanism and function of mitogen-activated protein kinase activation by ARF1. Cell Signal. 2015;27:2035-2044 pubmed publisher

product information

Product ID :

ADI-CSA-450

Catalog Number :

ADI-CSA-450-D

Product Name :

ARF1 monoclonal antibody (ARFS 3F1)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

50 µg

list of Pubmed id :

26169956

Clone :

ARFS 3F1

Isotype :

IgG2a

SPECIES REACTIVITY :

Human, Mouse, Rat, Sheep, Rabbit, Porcine, Monkey, Guinea pig, Dog, Chicken, Bovine

Background :

ADP-ribosylation factors (ARF) are a ubiquitous family of GTP-binding proteins involved in membrane dynamics and vesicular trafficking. The ARF family also includes the structurally related ARF-like proteins. ARF family members possess a highly conserved structure and function in eukaryotes. ARFs function as essential proteins in Saccharomyces cerevisiae (ARF-1 and ARF-2) and in Drosophila melanogaster (ARF-like). Many studies associate ARF proteins with exocytic and endocytic transport pathways, and the activation of phospholipase D activity. ARF-1, an abundantly expressed Ras-like N-myristoylated GTP-binding protein, co-purifies with tightly bound GDP. ARF possesses an extra β-strand (β2E) and N-terminal helix, two structural elements missing in Ras. Like Ras, ARF-1 switches between the GTP-bound “on” state where it transfers signals to its effectors in the signaling pathway, and the GDP-bound “off” state.

ALTnames :

ADP ribosylation factor 1

Immunogen :

Synthetic peptide corresponding to the sequence near the C-terminus of human ARF1.

Buffer :

Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.

Uses :

Detects a band of ~22kDa by Western blot.

Application Summary :

Storage :

-20°C