c-FLIP polyclonal antibody | Enzo Life Sciences ADI-AAP-440-E product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

c-FLIP polyclonal antibody

catalog :

ADI-AAP-440-E

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

product information

Product ID :

ADI-AAP-440

Catalog Number :

ADI-AAP-440-E

Product Name :

c-FLIP polyclonal antibody

Host species :

Rabbit

Clonality :

Polyclonal

Product Type :

Antibody

Size :

100 µg

list of Pubmed id :

26492363, 26261530, 26130327

SPECIES REACTIVITY :

Human, Mouse, Rat

Background :

The cellular FLICE-like inhibitory protein, cFLIP, is a cellular homologue of the viral protein, vFLIP. cFLIP contains two death effector domains (DEDs) and is expressed as either a short or long splice variant called cFLIPs and cFLIPL, respectively. cFLIP acts as a caspase-8 dominant negative regulator, blocking apoptosis induced by the oligimerization of the adapter protein, FADD. cFLIP interacts with FADD and caspase-8 through their respective DEDs.

ALTnames :

CASPER, CLARP, I-FLICE, Usurpin

Immunogen :

Synthetic peptide corresponding to the sequence near the N-terminus of human c-FLIP6. The sequence conserved among all c-FLIP variants.

Buffer :

Liquid. In PBS containing 0.02% sodium azide.

Uses :

Detects a band of ~28-58kDa by Western blot.

Application Summary :

ICC, WB

Storage :

+4°C