This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Mcl-1 polyclonal antibody
catalog :
ADI-AAP-240-F
quantity :
200 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
application :
western blot, immunohistochemistry, immunocytochemistry
citations: 2
Reference
Heinicke U, Kupka J, Fichter I, Fulda S. Critical role of mitochondria-mediated apoptosis for JNJ-26481585-induced antitumor activity in rhabdomyosarcoma. Oncogene. 2016;35:3729-41 pubmed publisher
Gaudette B, Dwivedi B, Chitta K, Poulain S, Powell D, Vertino P, et al. Low expression of pro-apoptotic Bcl-2 family proteins sets the apoptotic threshold in Waldenström macroglobulinemia. Oncogene. 2016;35:479-90 pubmed publisher
product information
Product ID :
ADI-AAP-240
Catalog Number :
ADI-AAP-240-F
Product Name :
Mcl-1 polyclonal antibody
Host species :
Rabbit
Clonality :
Polyclonal
Product Type :
Antibody
Size :
200 µg
list of Pubmed id :
26616861, 26024389, 25893290
SPECIES REACTIVITY :
Human, Rabbit, Porcine, Monkey, Guinea pig, Dog
Background :
Mcl-1 is a member of the Bcl-2 family that possesses anti-apoptotic activity. Mcl-1 is an immediate-early gene activated by the GMCSF as well as IL-3 signaling pathways and plays an important role in the viability response of these cytokines. Similar to all Bcl-2 family members, Mcl-1 contains BH1, BH2, and BH3 domains; however, unlike other members of this family, Mcl-1 has an extended N-terminal domain rich in PEST sequences, which probably accounts for the short half-life of this protein.
ALTnames :
Bcl-2-like protein 3
Immunogen :
Synthetic peptide corresponding to a portion of human Mcl-1.
Buffer :
Liquid. In PBS containing 0.09% sodium azide.
Uses :
Detects a band of ~42/43kDa by Western blot.
Application Summary :
IF, IHC (PS), WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.