Caspase-4 polyclonal antibody | Enzo Life Sciences ADI-AAP-104-C product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Caspase-4 polyclonal antibody

catalog :

ADI-AAP-104-C

quantity :

25 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

Product ID :

ADI-AAP-104

Catalog Number :

ADI-AAP-104-C

Product Name :

Caspase-4 polyclonal antibody

Host species :

Rabbit

Clonality :

Polyclonal

Product Type :

Antibody

Size :

25 µg

SPECIES REACTIVITY :

Human, Monkey

Background :

The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

Immunogen :

Synthetic peptide corresponding to a portion of human Caspase-4.

Buffer :

Liquid. In borate buffered saline, pH 8.2, containing 25mM sodium borate, 100mM boric acid, 75mM sodium chloride, and 5mM EDTA (disodium salt).

Uses :

Detects a band of ~45kDa by Western blot.

Application Summary :

Storage :

-20°C