This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Bag-1 monoclonal antibody (4A2)
catalog :
ADI-AAM-400-E
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4A2
reactivity :
human, mouse, rat
application :
western blot
citations: 1
Reference
Veit G, Oliver K, Apaja P, Perdomo D, Bidaud Meynard A, Lin S, et al. Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect. PLoS Biol. 2016;14:e1002462 pubmed publisher
product information
Product ID :
ADI-AAM-400
Catalog Number :
ADI-AAM-400-E
Product Name :
Bag-1 monoclonal antibody (4A2)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
Clone :
4A2
Isotype :
IgG
SPECIES REACTIVITY :
Human, Mouse, Rat
Background :
Bag-1 is a multifunctional Bcl-2-binding protein that lacks sequence homology with Bcl-2 and its related proteins, and functions to enhance the anti-apoptotic effects of Bcl-2. Bag-1 binds to the intracellular domain of the hepatocyte growth factor (HGF) and platelet-derived growth factor (PDGF) receptors, enhancing growth factor mediated protection from apoptosis. Bag-1 is known to modulate the chaperone activity of Hsc70/Hsp70, serving as a nucleotide exchange factor via binding to the ATPase domain of Hsc70/Hsp70. Bag-1 is known to promote cell survival through activation of the Raf-1 kinase.
ALTnames :
Bcl-2 associated athanogene-1, BAG family molecular chaperone regulator 1, RAP46
Immunogen :
Recombinant mouse Bag-1.
Buffer :
Liquid. In PBS, pH 7.2, containing 50% glycerol.
Uses :
Detects a band of ~28kDa (mouse and rat), ~31kDa (human) by Western blot.
Application Summary :
WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.