This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
DFF45/ICAD monoclonal antibody (6B8)
catalog :
ADI-AAM-382-E
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6B8

The same clone is also sold as:
reactivity :
human
application :
western blot
product information
Product ID :
ADI-AAM-382
Catalog Number :
ADI-AAM-382-E
Product Name :
DFF45/ICAD monoclonal antibody (6B8)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
Clone :
6B8
Isotype :
IgG1
SPECIES REACTIVITY :
Human
Background :
Human DNA fragmentation fragment (DFF) 45 and its mouse homologue caspase activated deoxyribonuclease (ICAD) are the inhibitors of DFF40 and CAD, respectively. DFF is composed of two subunits, DFF40/CAD and DFF45/ICAD. Cleavage of DFF45/ICAD, which is mediated by caspase-3, leads to DFF40/CADs activation as a nuclease. Activation of DFF40/CAD, which causes DNA degradation, is the hallmark of apoptotic cell death. DFF40 mRNA is expressed in a limited number of human tissues; pancreas, spleen, prostate, and ovary.
ALTnames :
CAD
Immunogen :
Recombinant human DFF45.
Buffer :
Lyophilized. In PBS, pH 7.2, containing 1% sucrose.
Uses :
Detects a band of ~45kDa (DFF45/ICAD-L) and ~40kDa (DFF45/ICAD-S) by Western blot.
Application Summary :
WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.