FADD monoclonal antibody (1F7) | Enzo Life Sciences ADI-AAM-212-E product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

FADD monoclonal antibody (1F7)

catalog :

ADI-AAM-212-E

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1F7

reactivity :

human, mouse

application :

western blot

more info or order :

Enzo Life Sciences product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 1c	Greenlee Wacker M, Kremserová S, Nauseef W. Lysis of human neutrophils by community-associated methicillin-resistant Staphylococcus aureus. Blood. 2017;129:3237-3244 pubmed publisher
western blot; human; loading ...; fig 2b	Lafont E, Kantari Mimoun C, Dráber P, De Miguel D, Hartwig T, Reichert M, et al. The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. EMBO J. 2017;36:1147-1166 pubmed publisher
western blot; mouse; 1:1000; fig 5	Chhibber Goel J, Coleman Vaughan C, Agrawal V, Sawhney N, Hickey E, Powell J, et al. Î³-Secretase Activity Is Required for Regulated Intramembrane Proteolysis of Tumor Necrosis Factor (TNF) Receptor 1 and TNF-mediated Pro-apoptotic Signaling. J Biol Chem. 2016;291:5971-85 pubmed publisher
	Vlantis K, Wullaert A, Polykratis A, Kondylis V, Dannappel M, Schwarzer R, et al. NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-ÎºB-Dependent and -Independent Functions. Immunity. 2016;44:553-567 pubmed publisher
	Zhao Y, Ma C, Wu L, Iwai K, Ashwell J, Oltz E, et al. CYLD and the NEMO Zinc Finger Regulate Tumor Necrosis Factor Signaling and Early Embryogenesis. J Biol Chem. 2015;290:22076-84 pubmed publisher

product information

Product ID :

ADI-AAM-212

Catalog Number :

ADI-AAM-212-E

Product Name :

FADD monoclonal antibody (1F7)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

list of Pubmed id :

26224629

Clone :

1F7

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Mouse

Background :

Fas-associating death domain containing protein (FADD)/MORT1 serves as a signal transducer of Fas-induced apoptosis. Through its amino-terminal death effector domain (DED), FADD binds to cytosolic proteins such as TRADD, a cytosolic death domaincontaining protein that asssociates with the cytosolic portion of TNF receptor, or MACH/FLICE/caspase-8, a protease with sequence homology to ICE-CED-3 protease family, in order to transduce the death signal.

ALTnames :

MORT1, Fas (TNFRSF6)-associated via death domain

Immunogen :

Recombinant human FADD.

Buffer :

Liquid. In PBS containing 50% glycerol.

Uses :

Detects a band of ~28kDa by Western blot.

Application Summary :

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage