Caspase-9 monoclonal antibody (2-22) | Enzo Life Sciences ADI-AAM-149-C product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Caspase-9 monoclonal antibody (2-22)

catalog :

ADI-AAM-149-C

quantity :

25 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2-22

The same clone is also sold as:

BD Biosciences: 551247, 551246

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation

citations: 1

Reference
Frese S, Pirnia F, Miescher D, Krajewski S, Borner M, Reed J, et al. PG490-mediated sensitization of lung cancer cells to Apo2L/TRAIL-induced apoptosis requires activation of ERK2. Oncogene. 2003;22:5427-35 pubmed

product information

Product ID :

ADI-AAM-149

Catalog Number :

ADI-AAM-149-C

Product Name :

Caspase-9 monoclonal antibody (2-22)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

25 µg

list of Pubmed id :

12934102

Image Legend 4 :

IHC Analysis: Human spleen tissue stained with Caspase-9, mAb (2-22) at 10ug/ml.

Clone :

2-22

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Monkey

Background :

The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

Immunogen :

Recombinant human Caspase-9 protein (prodomain).

Buffer :

Liquid. In PBS containing 0.01mM PMSF and 50% glycerol.

Application Summary :

IHC (PS), IP, WB

Storage :

-20°C