XIAP monoclonal antibody (2F1) | Enzo Life Sciences ADI-AAM-050-E product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

XIAP monoclonal antibody (2F1)

catalog :

ADI-AAM-050-E

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2F1

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunoprecipitation

citations: 4

Reference
Son Y, Kim E, Kim J, Kim S, Kwon T, Yoon A, et al. Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin. Cancer Res. 2007;67:8274-84 pubmed
Saito A, Hayashi T, Okuno S, Ferrand Drake M, Chan P. Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia. J Cereb Blood Flow Metab. 2003;23:1010-9 pubmed
Jia L, Patwari Y, Kelsey S, Srinivasula S, Agrawal S, Alnemri E, et al. Role of Smac in human leukaemic cell apoptosis and proliferation. Oncogene. 2003;22:1589-99 pubmed
Yamaguchi K, Nagai S, Ninomiya Tsuji J, Nishita M, Tamai K, Irie K, et al. XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. EMBO J. 1999;18:179-87 pubmed

product information

Product ID :

ADI-AAM-050

Catalog Number :

ADI-AAM-050-E

Product Name :

XIAP monoclonal antibody (2F1)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

list of Pubmed id :

17804742, 12973017, 12642862, 9878061, 9878061

Clone :

2F1

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Mouse

Background :

XIAP (X-linked inhibitor of apoptosis) belongs to the IAP (inhibitors of apoptosis) family, which is characterized by one or more BIR (baculovirus IAP repeat) domains. These proteins have multiple biological functions that include binding and inhibiting caspases, regulating cell cycle progression, and modulating receptor-mediated signal transduction. XIAP functions by direct binding and inhibition of several caspases, including caspase-3, caspase-7 and caspase-9.

ALTnames :

X-chromosome-linked inhibitor of apoptosis protein

Immunogen :

Recombinant human XIAP.

Buffer :

Liquid. In PBS, pH 7.2, containing 50% glycerol.

Uses :

Detects a band of ~55kDa by Western blot.

Application Summary :

IHC, IP, WB

Storage :

-20°C