Cathepsin D (human), (recombinant) (His-tag) | Enzo Life Sciences ADI-908-241-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

Cathepsin D (human), (recombinant) (His-tag)

catalog :

ADI-908-241-010

quantity :

10 µg

product information

Product ID :

ADI-908-241

Catalog Number :

ADI-908-241-010

Product Name :

Cathepsin D (human), (recombinant) (His-tag)

Product Type :

Protein

Size :

10 µg

Background :

Cathepsin D is an aspartyl endoproteinase distributed to the lysosome that participates in the degradation of proteins at an acidic pH. The proteolytic activity of Cathepsin D is known to play a role in antigen processing, cell proliferation and tissue renewal, and prohormone activation. Synthesized as a 54 kDa precursor, Cathepsin D is then proteolytically processed to an intermediate 48 kDa single chain which matures into more stable 34 kDa (heavy chain) and 14 kDa (light chain) subunits. As an estrogen-regulated lysosomal protease, overexpression of Cathepsin D in breast cancer is known to correlate with increased metastatic potential and shorter patient survival.

Purity :

≥90% (SDS-PAGE)

Buffer :

Liquid. In 50mM TRIS-Acetate, pH 7.5, containing 1mM EDTA and 20% glycerol.

Uses :

Western blot control.

Application Summary :

ELISA, WB, Inhibition assay

Storage :

-80°C