TNF-α (human), (recombinant) | Enzo Life Sciences ADI-908-066-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

TNF-α (human), (recombinant)

catalog :

ADI-908-066-010

quantity :

10 µg

product information

Product ID :

ADI-908-066

Catalog Number :

ADI-908-066-010

Product Name :

TNF-α (human), (recombinant)

Product Type :

Protein

Size :

10 µg

Background :

Tumor necrosis factor-alpha (TNFa), also known as cachectin, is a 17.5 kDa, 157 amino acid member of the TNF superfamily of cytokines that is a potent lymphoid factor with effects on a wide range of target cells. Active TNFa is produced as both soluble and membrane-anchored trimers by macrophages, NK cells, and T- and B-lymphocytes. TNF exerts proinflammatory signals via binding and inducing trimerization of TNF-receptor 1 (TNFR1) expressed on most normal and transformed cells, or to TNF-receptor 2 (TNFR2), expressed on endothelial and most immune cells. TNF signaling regulates hematopoiesis differentiation, endothelial cell activation, apoptosis, lipid metabolism, tumor progression, and immune surveillance, and dysregulation of TNF or its receptors is implicated in numerous disease states including cancer, osteoporosis, autoimmune diseases, diabetes, and atherosclerosis.

ALTnames :

Tumor necrosis factor-α, TNFSF 2

Purity :

≥98% (SDS-PAGE; RP-HPLC)

Buffer :

Lyophilized. Sterile filtered liquid, pH 7.2, containing 20mM PBS and 10mM sodium chloride.

Uses :

Western blot control.

Application Summary :

ELISA, WB, in vitro Assay

Storage :

-20°C