Jnk1 monoclonal antibody (2C6) | Enzo Life Sciences ADI-905-894-100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Jnk1 monoclonal antibody (2C6)

catalog :

ADI-905-894-100

quantity :

100 µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2C6

The same clone is also sold as:

Cell Signaling Technology: 3708

reactivity :

human

application :

western blot

product information

Product ID :

ADI-905-894

Catalog Number :

ADI-905-894-100

Product Name :

Jnk1 monoclonal antibody (2C6)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µl

Clone :

2C6

Isotype :

IgG1

SPECIES REACTIVITY :

Human

Background :

JNK1 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK1 is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of JNK1 by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. JNK1 is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of JNK1 gene suggested that it play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

ALTnames :

c-Jun N-terminal kinase 1, SAP kinase 1c, SAPK1c, MAP kinase 8, MAPK8

Immunogen :

Recombinant human Jnk1 (aa 1-384).

Buffer :

Liquid. In PBS, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Uses :

Detects a band of ~45kDa (full length) by Western blot.

Application Summary :

Storage :

-20°C