α-Actinin monoclonal antibody (7A4) | Enzo Life Sciences ADI-905-891-100 product information

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product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

α-Actinin monoclonal antibody (7A4)

catalog :

ADI-905-891-100

quantity :

100 µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7A4

reactivity :

human

application :

western blot

product information

Product ID :

ADI-905-891

Catalog Number :

ADI-905-891-100

Product Name :

α-Actinin monoclonal antibody (7A4)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µl

Clone :

7A4

Isotype :

IgG2a

SPECIES REACTIVITY :

Human

Background :

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.

ALTnames :

ACTN1

Immunogen :

Recombinant human α-actinin (aa 650-893).

Buffer :

Liquid. In PBS, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Uses :

Detects a band of ~98kDa (full length) by Western blot.

Application Summary :

Storage :

-20°C