This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Septin 5/Cdcrel-1 monoclonal antibody (SP18)
catalog :
ADI-905-781-100
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
SP18

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
product information
Product ID :
ADI-905-781
Catalog Number :
ADI-905-781-100
Product Name :
Septin 5/Cdcrel-1 monoclonal antibody (SP18)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
Clone :
SP18
Isotype :
IgG1
SPECIES REACTIVITY :
Human, Mouse, Rat
Background :
Septin 5 (Sept5/CDCrel-1) is a member of the Septin family of cytoskeletal GTPases. Septin 5 expression is primarily associated with synaptic vesicles in cells of the nervous system where it acts to inhibit exocytosis, although it has also been characterized as an inhibitor of aggregation and release of storage granules in platelets. Phosphorylation of Septin 5 at Ser17 by Cdk5-p35 has been shown to mediate the interaction of Septin 5 with the SNARE protein Syntaxin-1A, regulating neurotransmitter release. Targeted disruption of the Septin 5 gene in mice failed to produce an obvious neurological phenotype, indicating its loss may be overcome by functional redundancy of other septins. Septin 5 is one of several Parkin (an E3 ubiquitin ligase) associated substrates whose accumulation results in cellular toxicity related to the onset of autosomal recessive Parkinson Disease.
Immunogen :
Immunoprecipitate of human brain.
Buffer :
Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Uses :
Detects a band of ~43kDa by Western blot.
Application Summary :
IHC (PS), WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.