This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Angiotensin II receptor AT1 polyclonal antibody
catalog :
ADI-905-743-100
quantity :
100 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry
product information
Product ID :
ADI-905-743
Catalog Number :
ADI-905-743-100
Product Name :
Angiotensin II receptor AT1 polyclonal antibody
Host species :
Rabbit
Clonality :
Polyclonal
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
23515786
Image Legend 4 :
Immunohistochemistry analysis: Rat brain nucleus tractis solitarus fixed with 100% methanol and stained with propidium iodide (red) and Angiotensin II Receptor (AT1) pAb at 1:1000 (green).
Image Legend 5 :
Western blot analysis: MW marker (1) and 20ug of kidney membrane extract (2) probed with Angiotensin II Receptor (AT1) pAb at 3 ug/ml.
SPECIES REACTIVITY :
Human, Mouse, Rat
Background :
The actions of the octapeptide circulatory hormone angiotensin II are mediated by type one (AT1) and type two (AT2) angiotensin II receptors, members of the seven-transmembrane domain-containing GPCR family. AT1 expression is greatest in vascular smooth muscle, liver, kidney, adrenal cortex, brain, and lung, and is primarily responsible for the physiological effects of angiotensin II in cardiovascular homeostasis. The AT2 receptor displays approximately 30% identity to the AT1 receptor, and is highly expressed during embryonic development. AT2 expression in adult tissue is limited to the adrenal medulla, brain, and reproductive tissues, but is upregulated in injured tissue following myocardial infarction, vascular injury, and wound healing.
ALTnames :
AGTR1
Immunogen :
Synthetic peptide corresponding to the sequence near the N-terminus of rat angiotensin II receptor AT1.
Buffer :
Liquid. In PBS containing 50% glycerol and 0.01% sodium azide.
Uses :
Suitable for cell-based and membrane-based ELISA. Predicted MW of ~41kDa. Higher MW species (~55kDa) and intermediates also observed by Western blot which reflect post-translational modification and dimerization of the receptor.
Application Summary :
ELISA, IHC, WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.