This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
mTOR polyclonal antibody
catalog :
ADI-905-687-100
quantity :
100 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot
product information
Product ID :
ADI-905-687
Catalog Number :
ADI-905-687-100
Product Name :
mTOR polyclonal antibody
Host species :
Rabbit
Clonality :
Polyclonal
Product Type :
Antibody
Size :
100 µg
SPECIES REACTIVITY :
Human, Mouse
Background :
Mammalian target of rapamycin (mTOR) is an atypical serine-threonine protein kinase and member of the phosphatidylinositol 3-kinase (PI3K) signaling pathway. TORC1 (mTOR, GβL/mLST8 and Raptor) and TORC2 (mTOR, GβL/mLST8, SIN1, and Rictor) complexes control protein synthesis through the direct or indirect phosphorylation of downstream targets such as S6 Kinase and 4EBP1, key regulators of mRNA recruitment to ribosomes. Through its involvement in several key signaling pathways and its critical role in transcription and translation, mTOR mediates cell proliferation, differentiation, and survival. Studies identified the TORC2 complex as the missing kinase activator of Akt/PKB, deregulation of which has been implicated in the pathogenesis of cancer and diabetes.
ALTnames :
FRAP, FK506 binding protein 12-rapamycin associated protein
Immunogen :
Synthetic peptide corresponding to a portion of human mTOR.
Buffer :
Liquid. In TRIS, pH 7.2, containing 0.09% sodium azide and 50% glycerol.
Uses :
Detects a band of ~289kDa by Western blot.
Application Summary :
WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.