This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Caspase-9 monoclonal antibody (10-1-87)
catalog :
ADI-905-686-100
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10-1-87

The same clone is also sold as:
reactivity :
human
application :
western blot
citations: 2
Reference
Marsden V, Kaufmann T, O Reilly L, Adams J, Strasser A. Apaf-1 and caspase-9 are required for cytokine withdrawal-induced apoptosis of mast cells but dispensable for their functional and clonogenic death. Blood. 2006;107:1872-7 pubmed
Kelly J, Waterhouse N, Cretney E, Browne K, Ellis S, Trapani J, et al. Granzyme M mediates a novel form of perforin-dependent cell death. J Biol Chem. 2004;279:22236-42 pubmed
product information
Product ID :
ADI-905-686
Catalog Number :
ADI-905-686-100
Product Name :
Caspase-9 monoclonal antibody (10-1-87)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
16291596, 15028722
Clone :
10-1-87
Isotype :
IgG2a
SPECIES REACTIVITY :
Human
Background :
The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.
Immunogen :
Recombinant full length human Caspase-9.
Buffer :
Liquid. In PBS, pH 7.2, containing 0.09% sodium azide and 50% glycerol.
Uses :
Detects bands of ~47kDa (full length) and ~37/35kDa (cleaved) by Western blot.
Application Summary :
WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.