[pSer133]CREB monoclonal antibody (10E9) | Enzo Life Sciences ADI-905-639-100 product information

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product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

[pSer133]CREB monoclonal antibody (10E9)

catalog :

ADI-905-639-100

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

10E9

reactivity :

human, mouse, dogs

application :

western blot, ELISA

product information

Product ID :

ADI-905-639

Catalog Number :

ADI-905-639-100

Product Name :

[pSer133]CREB monoclonal antibody (10E9)

Host species :

Mouse

Clonality :

Monoclonal

Antigen modification :

Phosphorylated

Product Type :

Antibody

Size :

100 µg

Clone :

10E9

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Mouse, Dog

Background :

The transcription factor CREB (cAMP response element binding) binds the palindromic octanucleotide TGACGTCA. Members of the ATF/CREB family include CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2, and ATF-3. Phosphorylation of CREB allows recruitment of CREB-binding protein (CBP), a large co-activator that contacts the general transcriptional machinery. CREB-mediated transcription regulates diverse cellular responses, including intermediary metabolism, neuronal signaling, cell proliferation, and apoptosis.

ALTnames :

cAMP responsive element binding protein

Immunogen :

Synthetic peptide corresponding to a portion of CREB phosphorylated at Ser133.

Buffer :

Lyophilized from 1ml of 2x PBS containing 0.09% sodium azide, PEG, and sucrose.

Uses :

Detects bands of ~43kDa (CREB) and ~38kDa (ATF1) by Western blot.

Application Summary :

ELISA, WB

Storage :

-20°C