RIP3 polyclonal antibody | Enzo Life Sciences ADI-905-242-100 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

RIP3 polyclonal antibody

catalog :

ADI-905-242-100

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, western blot knockout validation

more info or order :

Enzo Life Sciences product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; loading ...; fig 3b	Siegmund D, Ehrenschwender M, Wajant H. TNFR2 unlocks a RIPK1 kinase activity-dependent mode of proinflammatory TNFR1 signaling. Cell Death Dis. 2018;9:921 pubmed publisher
western blot knockout validation; mouse; loading ...; fig s1f	Van T, Polykratis A, Straub B, Kondylis V, Papadopoulou N, Pasparakis M. Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. J Clin Invest. 2017;127:2662-2677 pubmed publisher
western blot; mouse; loading ...; fig 4c	Krishna Subramanian S, Singer S, Armaka M, Banales J, Hölzer K, Schirmacher P, et al. RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury. Cell Death Differ. 2019;: pubmed publisher
western blot; mouse; loading ...; fig 2b	Peltzer N, Darding M, Montinaro A, Dráber P, Draberova H, Kupka S, et al. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. Nature. 2018;557:112-117 pubmed publisher
western blot; mouse; 1:1000; fig s1d	Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, et al. Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency. Nat Cell Biol. 2017;19:1116-1129 pubmed publisher
western blot; mouse; loading ...; fig 4b	Lafont E, Kantari Mimoun C, Dráber P, De Miguel D, Hartwig T, Reichert M, et al. The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death. EMBO J. 2017;36:1147-1166 pubmed publisher
western blot; mouse; fig 3	Lin J, Kumari S, Kim C, Van T, Wachsmuth L, Polykratis A, et al. RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Nature. 2016;540:124-128 pubmed publisher
western blot; mouse; fig 4b	Vlantis K, Wullaert A, Polykratis A, Kondylis V, Dannappel M, Schwarzer R, et al. NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-ÎºB-Dependent and -Independent Functions. Immunity. 2016;44:553-567 pubmed publisher
	Korwitz A, Merkwirth C, Richter Dennerlein R, TrÃ¶der S, Sprenger H, QuirÃ³s P, et al. Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria. J Cell Biol. 2016;212:157-66 pubmed publisher

product information

Product ID :

ADI-905-242

Catalog Number :

ADI-905-242-100

Product Name :

RIP3 polyclonal antibody

Host species :

Rabbit

Clonality :

Polyclonal

Product Type :

Antibody

Size :

100 µg

SPECIES REACTIVITY :

Mouse, Rat

Background :

A member in the RIP kinase family was identified and designated RIP3 (Receptor-interacting serine/threonine protein kinase-3). RIP3 contains an N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNF-R1, mediates TNF-R1 induced apoptosis, and attenuates RIP and TNF-R1 induced NF-κB activation.

ALTnames :

Receptor-interacting serine/threonine protein kinase 3, RIP-like protein kinase 3, Receptor-interacting protein 3

Immunogen :

Synthetic peptide corresponding to a portion of mouse RIP3.

Buffer :

Liquid. In PBS containing 0.02% sodium azide.

Uses :

Detects a band of ~57kDa by Western blot.

Application Summary :

IHC (PS), WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage