This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
TRAIL-R3 polyclonal antibody
catalog :
ADI-905-216-100
quantity :
100 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunocytochemistry
product information
Product ID :
ADI-905-216
Catalog Number :
ADI-905-216-100
Product Name :
TRAIL-R3 polyclonal antibody
Host species :
Rabbit
Clonality :
Polyclonal
Product Type :
Antibody
Size :
100 µg
SPECIES REACTIVITY :
Human, Mouse, Rat
Background :
Decoy receptors (DcRs) are signaling-deficient receptors for certain members of the TNF family of cytokines, including TRAIL/Apo2L and FasL. Functional TRAIL receptors such as DR4 and DR5 transmit apoptotic signals via their intracellular death domains. In contrast, three identified TRAIL decoy receptors (DcR1, DcR2, and osteoprotegerin/OPG) completely or partially lack the signaling death domain, and/or are secreted from cells and unable to transmit intracellular signals. Thus, expression of DcRs promotes survival by sequestration of apoptotic ligands. A fourth identified decoy receptor, DcR3, binds both FasL and the vascular endothelial cell growth inhibitor (VEGI), inhibiting Fas and DR3 death signals.
ALTnames :
TRAIL receptor 3, DcR1, Death Receptor 1, TRID, CD263, TNFRSF 10C, TNF-related apoptosis-inducing ligand receptor 3, Tumor necrosis factor receptor superfamily member 10C
Immunogen :
Synthetic peptide corresponding to a portion of the extracellular domain of human TRAIL-R3.
Buffer :
Liquid. In PBS containing 0.02% sodium azide.
Uses :
Detects a band of ~65kDa by Western blot.
Application Summary :
ICC, WB
Storage :
+4°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.