LTB4 ELISA kit | Enzo Life Sciences ADI-901-068 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

ELISA/assay

product name :

LTB4 ELISA kit

catalog :

ADI-901-068

quantity :

5 x 96 wells

citations: 14

Reference
Park J, Park S, Kim J. Leukotriene B4 receptor-2 contributes to chemoresistance of SK-OV-3 ovarian cancer cells through activation of signal transducer and activator of transcription-3-linked cascade. Biochim Biophys Acta. 2016;1863:236-43 pubmed publisher
Gajos K, Kozdrowski R, Nowak M, Siemieniuch M. Altered secretion of selected arachidonic acid metabolites during subclinical endometritis relative to estrous cycle stage and grade of fibrosis in mares. Theriogenology. 2015;84:457-66 pubmed publisher
Lee A, Cho K, Kim J. MyD88-BLT2-dependent cascade contributes to LPS-induced interleukin-6 production in mouse macrophage. Exp Mol Med. 2015;47:e156 pubmed publisher
Silwal P, Shin K, Choi S, Kang S, Park J, Lee H, et al. Adenine suppresses IgE-mediated mast cell activation. Mol Immunol. 2015;65:242-9 pubmed publisher
Trindade B, Theriot C, Leslie J, Carlson P, Bergin I, Peters Golden M, et al. Clostridium difficile-induced colitis in mice is independent of leukotrienes. Anaerobe. 2014;30:90-8 pubmed publisher
Roos J, Oancea C, Heinssmann M, Khan D, Held H, Kahnt A, et al. 5-Lipoxygenase is a candidate target for therapeutic management of stem cell-like cells in acute myeloid leukemia. Cancer Res. 2014;74:5244-55 pubmed publisher
Kutil Z, Temml V, Maghradze D, Pribylova M, Dvoráková M, Schuster D, et al. Impact of wines and wine constituents on cyclooxygenase-1, cyclooxygenase-2, and 5-lipoxygenase catalytic activity. Mediators Inflamm. 2014;2014:178931 pubmed publisher
di Meco A, Lauretti E, Vagnozzi A, Pratico D. Zileuton restores memory impairments and reverses amyloid and tau pathology in aged Alzheimer's disease mice. Neurobiol Aging. 2014;35:2458-2464 pubmed publisher
Galet C, Gollapudi K, Stepanian S, Byrd J, Henning S, Grogan T, et al. Effect of a low-fat fish oil diet on proinflammatory eicosanoids and cell-cycle progression score in men undergoing radical prostatectomy. Cancer Prev Res (Phila). 2014;7:97-104 pubmed publisher
Lin W, Huang M, Xue X, Bertelsen K, Chen G, Zhao H, et al. A highly sensitive and selective method for the determination of leukotriene B4 (LTB4) in ex vivo stimulated human plasma by ultra fast liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2013;925:54-62 pubmed publisher
Panossian A, Hambardzumyan M, Hovhanissyan A, Wikman G. The adaptogens rhodiola and schizandra modify the response to immobilization stress in rabbits by suppressing the increase of phosphorylated stress-activated protein kinase, nitric oxide and cortisol. Drug Target Insights. 2007;2:39-54 pubmed
Nam Y, Min D, Kim H, Song K, Kim K, Lee Y, et al. Leukotriene B4 receptor BLT-mediated phosphorylation of NF-?B and CREB is involved in IL-8 production in human mast cells induced by Trichomonas vaginalis-derived secretory products. Microbes Infect. 2011;13:1211-20 pubmed publisher
Chu J, Pratico D. Pharmacologic blockade of 5-lipoxygenase improves the amyloidotic phenotype of an Alzheimer's disease transgenic mouse model involvement of ?-secretase. Am J Pathol. 2011;178:1762-9 pubmed publisher
Steel H, Tintinger G, Anderson R. Comparison of the anti-inflammatory activities of imidazole antimycotics in relation to molecular structure. Chem Biol Drug Des. 2008;72:225-8 pubmed

product information

Product ID :

ADI-901-068

Catalog Number :

ADI-901-068

Product Name :

LTB4 ELISA kit

Product Type :

Kit

Size :

5 x 96 wells

list of Pubmed id :

26597704, 25963128, 25838003, 25700347, 25230329, 25082812, 24976682, 24973121, 24169960, 23523878

Product Description :

The LTB4 EIA kit is a colorimetric competitive enzyme immunoassay kit with results in 4 hours. Absorbance is read at 405 nm. Assay up to 39 samples in duplicate with a broad dynamic range that is suitable for a wide variety of sample matrices. Document your results to scientists world-wide with this highly cited kit.

SPECIES REACTIVITY :

Species independent

Background :

Leukotrienes are major products of 5-lipoxygenase metabolism of arachidonic acid. Leukotriene B4 (LTB4) stimulates leukocyte functions including lysosomal enzyme release, adhesion, and aggregation of polymorphonuclear leukocytes. LTB4 has been implicated as a potent mediator of inflammatory diseases and immunoregulation. The cysteinyl leukotrienes (LTC4, LTD4, and LTE4) are formed by addition of cysteine derivatives to LTA4. The conversion of LTA4 to LTC4 by the enzyme LTC4 synthase limits the rate of cysteinyl leukotriene formation. Cysteinyl leukotrienes are potent lipid mediators in inflammation, inducing smooth muscle contractions and increased capillary permeability.

ALTnames :

Leukotriene B4

Uses :

For the quantitative determination of LTB4 in culture supernatants, plasma, saliva, and urine from any species. Cited sample types include bronchioalveolar lavage fluid, cell lysate, crevicular fluid, tissue, serum and whole blood.

Application Summary :

ELISA, Colorimetric detection