Bradykinin ELISA kit | Enzo Life Sciences ADI-900-206 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

ELISA/assay

product name :

Bradykinin ELISA kit

catalog :

ADI-900-206

quantity :

96 wells

citations: 3

Reference
Kageyama S, Hata K, Tanaka H, Hirao H, Kubota T, Okamura Y, et al. Intestinal ischemic preconditioning ameliorates hepatic ischemia/reperfusion injury in rats: role of heme oxygenase 1 in the second window of protection. Liver Transpl. 2015;21:112-22 pubmed publisher
Crawford T, Paushkin S, Kobayashi D, Forrest S, JOYCE C, Finkel R, et al. Evaluation of SMN protein, transcript, and copy number in the biomarkers for spinal muscular atrophy (BforSMA) clinical study. PLoS ONE. 2012;7:e33572 pubmed publisher
Kobayashi D, Olson R, Sly L, Swanson C, Chung B, Naryshkin N, et al. Utility of survival motor neuron ELISA for spinal muscular atrophy clinical and preclinical analyses. PLoS ONE. 2011;6:e24269 pubmed publisher

product information

Product ID :

ADI-900-206

Catalog Number :

ADI-900-206

Product Name :

Bradykinin ELISA kit

Product Type :

Kit

Size :

96 wells

list of Pubmed id :

22558076, 21904622

Product Description :

The Bradykinin EIA kit is a colorimetric, competitive immunoassay kit with results in 3 hours.

SPECIES REACTIVITY :

Species independent

Background :

Bradykinin was discovered in 1949 as a substance generated from a globulin precursor in plasma by the action of proteases. Its name indicates that is causes a slow movement of the gut. As early as 1909 it was noted that substances found in urine, which were later identified as kinins, have hypotensive actions. Kinins are effectors of vasodilation, vascular permeability, NO release and arachidonic acid mobilization. They are important regulators of blood pressure, kidney function and heart function, and they are also involved in inflammation. Bradykinin is generated from the blood globulin kininogen HK, by the action of the kallikrein system in blood (related to the blood clotting cascade) but can also be generated in other tissues and organs. Besides kallikrein, other proteases such as plasmin may also release bradykinin. Several peptidases can degrade kinins, includ-ing Angiotensin Converting Enzyme (ACE), a metalloproteinase which converts Angiotensin I to Angiotensin II and destroys bradykinin. Plasma bradykinin is rapidly degraded to a smaller stable peptide (BK1-5) form.

Uses :

For the quantitative determination of species independent Bradykinin in plasma, serum and urine samples.

Application Summary :

ELISA, Colorimetric detection

Storage :

-20°C