This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
ELISA/assay
product name :
IL-33 (human), ELISA kit
catalog :
ADI-900-201
quantity :
96 wells
citations: 1
Reference
Kakkar R, Hei H, Dobner S, Lee R. Interleukin 33 as a mechanically responsive cytokine secreted by living cells. J Biol Chem. 2012;287:6941-8 pubmed publisher
product information
Product ID :
ADI-900-201
Catalog Number :
ADI-900-201
Product Name :
IL-33 (human), ELISA kit
Product Type :
Kit
Size :
96 wells
list of Pubmed id :
22215666
Product Description :
The IL-33 (human), EIA kit is a colorimetric immunometric immunoassay kit with results in 3 hours.
SPECIES REACTIVITY :
Human
Background :
IL-33, also named Nuclear Factor from High Endothelial Venules (NF-HEV), is a member of the Interleukin-1 (IL-1) family. Members of this family, such as IL-1α/β and IL-18, are known to play important roles in host defense, immune regulation, neuronal injury and inflammation. IL-33 has been reported to be the specific ligand for ST24, an orphan receptor of the IL-1 receptor family. Stimulation of ST2 by IL-33 induces NF-κB and MAPK signaling pathways. IL-33 is synthesized in response to cytokines such as IL-1β and TNF-α and plays an important role in TH2-associated immunology by triggering increased secretion of IL-5 and IL-13 from polarized TH2 cells. IL-33 has also been found to be localized in the nucleus of human epithelial and endothelial cells, and can be present in serum and synovial fluid samples of patients with rheumatoid arthritis. Overexpression of IL-33 in mice has been found to induce asthmatic symptoms, and enhance joint inflammation.
ALTnames :
Interleukin-33, NF-HEV
Uses :
For the quantitative determination of human IL-33 in cell lysates, culture supernatants, serum, plasma and synovial fluid samples.
Application Summary :
ELISA, Colorimetric detection
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.